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    US Plasma Fractionation Market Share

    ID: MRFR/HC/13160-HCR
    200 Pages
    Rahul Gotadki
    September 2025

    US Plasma Fractionation Market Research Report By Product Type (Immunoglobulin, Albumin, Coagulation Factors, Protease Inhibitors), By Application (Neurology, Hematology, General Medicine, Immunology), By End User (Hospitals, Ambulatory Surgical Centers, Blood Banks, Pharmaceutical Companies) and By Technology (Centrifugation, Chromatography, Precipitation, Filtration)-Forecast to 2035

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    Market Share

    US Plasma Fractionation Market Share Analysis

    Another critical system in market share situating is key associations and coordinated efforts. Organizations perceive the significance of falling in line with key partners in the healthcare environment, like emergency clinics, centers, and drug wholesalers. By laying major areas of strength for out, they can get a dependable dispersion organization, upgrade market reach, and strengthen their brand presence. Joint efforts with healthcare experts and establishments similarly add to the improvement of inventive therapies and cultivate a positive standing inside the clinical local area, at last converting into expanded market share. Serious evaluating is a crucial component in market share situating. In the US plasma fractionation market, organizations decisively set costs for their items to speak to an expansive range of customers while maintaining benefit. Valuing techniques might include offering significant limits, group bargains, or executing a layered evaluating structure considering the volume of buys. Furthermore, organizations might investigate value based evaluating, where the expense of their items is justified by the one of a kind advantages they give, thereby permitting them to catch an exceptional market section. Market extension is another imperative system utilized by organizations in the plasma fractionation area. This includes recognizing and entering new geological markets or expanding product offerings to take care of a more extensive scope of ailments. By broadening their contributions and geographical presence, organizations can take advantage of previously undiscovered customer portions and lessen reliance on unambiguous markets. This assists in expanding market with sharing as well as upgrades versatility against territorial financial uncertainties and administrative changes.

    Market Summary

    The US Plasma Fractionation market is projected to grow from 4.77 USD billion in 2024 to 8.2 USD billion by 2035, reflecting a robust growth trajectory.

    Key Market Trends & Highlights

    US Plasma Fractionation Key Trends and Highlights

    • The market is expected to achieve a compound annual growth rate (CAGR) of 5.05 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 8.2 USD billion, indicating substantial growth potential.
    • In 2024, the market is valued at 4.77 USD billion, laying a strong foundation for future expansion.
    • Growing adoption of advanced plasma therapies due to increasing prevalence of chronic diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 4.77 (USD Billion)
    2035 Market Size 8.2 (USD Billion)
    CAGR (2025-2035) 5.05%
    Largest Regional Market Share in 2024 latin_america)

    Major Players

    Cerus Corporation, Octapharma, Kedrion, Grifols, Sandoz, Takeda Pharmaceutical, Baxter International, CSL Behring, Shire, Emergent BioSolutions, Thermo Fisher Scientific, Pfizer, AbbVie, American Red Cross, BioMerieux

    Market Trends

    The US Plasma Fractionation Market is driven by several key factors that influence its growth and development. The increasing prevalence of chronic diseases and the rising demand for immunoglobulin therapies significantly shape the market landscape. The growing number of hemophilia patients and the need for clotting factor concentrates further contribute to the demand for plasma-derived products. The U.S. government supports this sector through regulatory frameworks and funding initiatives, promoting safe and efficient plasma collection and fractionation processes. As more healthcare providers recognize the benefits of plasma therapies, the market continues to gain traction.

    There are also various opportunities to be explored within the US Plasma Fractionation Market. The advancement of technology in blood plasma processing and the development of new therapeutic applications offer potential avenues for expansion. Moreover, increasing awareness regarding rare diseases, which often require specific plasma-derived treatments, opens up pathways for innovative solutions. Collaborations between healthcare sectors, research institutions, and plasma collection centers could leverage shared expertise to improve treatment options. In recent times, trends such as the rise of specialty pharmacies and personalized medicine are gaining momentum.

    These trends impact how plasma products are marketed and distributed, tailoring approaches to meet the needs of individual patients more effectively. The focus on patient-centered care encourages product developers to innovate and enhance existing therapies. The continuous rise in the number of plasma donation centers in the U.S. illustrates a commitment to improving access to these life-saving treatments, further reflecting the dynamic nature of the Plasma Fractionation Market in the region.

    US Plasma Fractionation Market Market Drivers

    Market Segment Insights

    Plasma Fractionation Market Product Type Insights

    The US Plasma Fractionation Market, particularly in the Product Type segment, encompasses a diverse range of components that are crucial for therapeutic applications. Immunoglobulin is one of the most significant fractions, widely recognized for its role in treating various immune deficiencies and other related disorders. This segment holds a dominant position in the market due to its broad spectrum of clinical applications, including autoimmune diseases and infections, reflecting a growing demand among healthcare providers.

    Albumin, another vital product derived from plasma, is essential for fluid management in patients, especially those undergoing surgery or suffering from liver diseases. Its versatility and importance in critical care settings have contributed to its substantial market presence.

    Coagulation factors, which are essential in managing bleeding disorders such as hemophilia, present another critical aspect of the Plasma Fractionation Market. The increasing prevalence of these disorders has driven innovation and an expanding patient population in need of effective treatments, making this segment particularly significant for ongoing market growth. Additionally, protease inhibitors, though less widespread compared to Immunoglobulin and Albumin, play an essential role in addressing viral infections and inflammatory conditions.

    Their incorporation into treatment protocols has been pivotal, highlighting evolving therapeutic strategies rooted in plasma-derived products. Overall, the segmentation of the US Plasma Fractionation Market sheds light on how various product types serve specific medical needs, promoting considerable advancements in patient care and treatment efficacy across the healthcare spectrum.

    This market segment continues to evolve, harnessing technological innovations and increased awareness to drive growth opportunities while also adapting to regulatory landscapes and healthcare demands. As the healthcare infrastructure in the U.S. emphasizes improved treatment outcomes and specialized therapies, each product type within this market demonstrates its unique contributions and sustained relevance in shaping the future of plasma-derived therapeutics.

    Plasma Fractionation Market Application Insights

    The US Plasma Fractionation Market is a vital component of the healthcare industry, particularly in the Application segment, which encompasses various disciplines such as Neurology, Hematology, General Medicine, and Immunology. Neurology remains a crucial area due to the increasing prevalence of neurological disorders, where plasma-derived therapeutics play a significant role in treatment protocols. In Hematology, products derived from plasma fractionation are essential for managing blood-related conditions, showcasing the importance of this segment in patient care.

    General Medicine integrates diverse applications of plasma products, demonstrating their versatility and wide acceptance in clinical practices. Immunology is also a key focus, as the demand for immunoglobulin therapies continues to rise, reflecting the increasing awareness and diagnosis of autoimmune diseases. The growth in these applications is fueled by advancing medical technology, increased funding for Research and Development, and a rising geriatric population, which highlights the necessity for innovative treatment solutions.

    The ongoing development of new plasma-based therapies presents significant opportunities while navigating regulatory frameworks and supply chain challenges remains a key consideration within the industry landscape.

    Plasma Fractionation Market End User Insights

    The 'End User' segment of the US Plasma Fractionation Market is diverse, comprising key entities such as Hospitals, Ambulatory Surgical Centers, Blood Banks, and Pharmaceutical Companies. Hospitals are central to plasma fractionation as they provide critical care services that depend on plasma-derived products for treating various medical conditions. Ambulatory Surgical Centers play a crucial role by enhancing patient access to specialized treatments involving plasma therapies, thereby streamlining service delivery. Blood Banks are indispensable, serving as collection, testing, and distribution hubs for plasma, with stringent regulations in place to ensure safety and efficacy in handling blood components.

    Pharmaceutical Companies dominate the market by developing innovative therapies derived from plasma, thus driving advancements in treatment methodologies. The interplay of these users amid ongoing research and regulatory changes shapes the market landscape, with increasing demand for immunoglobulins and clotting factor concentrates underscoring their significance in healthcare. The ongoing improvements in processing technology and patient treatment protocols signal growth opportunities, while challenges related to supply chain management and regulatory compliance persist for these stakeholders.

    Plasma Fractionation Market Technology Insights

    The Technology segment of the US Plasma Fractionation Market plays a critical role in the effective separation and purification of plasma components, which is essential for various medical applications. Within this segment, Centrifugation stands out due to its efficiency in separating plasma proteins based on density, making it a widely used technique in laboratories. Chromatography is also significant as it provides high-resolution separation, critical for the purification of specific proteins required in therapies, reflecting increasing demand for more refined therapeutic products.

    Precipitation methods offer another avenue for isolating plasma proteins, leveraging changes in solubility, and are continuously evolving to enhance efficiency and yield in clinical settings. Finally, Filtration techniques are important for their ability to maintain sterility while selectively filtering plasma components, ensuring safe and effective usage in medical treatments. The continuous advancements in these technologies foster innovation within the US Plasma Fractionation Market, contributing to improved patient outcomes and addressing the growing need for therapeutics derived from human plasma.

    The integration of automation and real-time monitoring systems is also poised to enhance operational efficiency and regulatory compliance in this dynamic landscape.

    Get more detailed insights about US Plasma Fractionation Market Research Report-Forecast to 2035

    Regional Insights

    Key Players and Competitive Insights

    The US Plasma Fractionation Market is characterized by a dynamic competitive landscape where various players strive to enhance their portfolios and market positioning through innovation and expansion. As the global demand for plasma-derived medicinal products continues to grow, companies operating within this sector are focusing on advancing their technologies, improving operational efficiency, and expanding their capacity to meet healthcare needs.

    This market is influenced by factors such as regulatory frameworks, technological advancements, and the increasing prevalence of chronic diseases that necessitate the use of plasma-derived therapeutics. In addition, strategic partnerships and collaborations play a pivotal role as organizations seek to leverage collective strengths to innovate and enhance their market reach.

    Cerus Corporation stands out in the US Plasma Fractionation Market with its proprietary technologies that focus on pathogen reduction and blood safety. The company has established a credible presence through its innovative Intercept Blood System, which is designed to reduce the risk of transfusion-transmitted infections. With an emphasis on safety and efficacy, Cerus Corporation has garnered a strong reputation for its commitment to enhancing blood product quality.

    The company’s advancements in pathogen reduction technologies, along with a robust regulatory approval history, position it favorably among healthcare providers looking for reliable solutions. Additionally, Cerus Corporation has strategically positioned itself to expand its market share by aligning with various blood centers, thereby increasing its accessibility and operational footprint within the United States.

    Octapharma is another key player in the US Plasma Fractionation Market, known for its focus on producing high-quality human protein products derived from human plasma. The company emphasizes therapeutic areas, including hematology, immunotherapy, and intensive care, delivering a range of immunoglobulins, coagulation factors, and albumins that cater to diverse patient needs.

    Octapharma’s strong market presence in the U.S. is underlined by its commitment to research and development, allowing it to introduce innovative therapies adapting to evolving healthcare demands. The company has also engaged in significant mergers and acquisitions, fortifying its position within the market and expanding its product offerings. By collaborating with health organizations and maintaining a focus on quality assurance, Octapharma enhances its operational strengths, ensuring that it remains a trusted name in the plasma-derived medicinal product space.

    Key Companies in the US Plasma Fractionation Market market include

    Industry Developments

    Recent developments in the US Plasma Fractionation Market have highlighted a surge in interest and activity among key players. For instance, in August 2023, Cerus Corporation announced advancements in its INTERCEPT Blood System technology, aiming to enhance safety protocols in plasma transfusions.

    In July 2023, Grifols expanded its production capacity in North Carolina to meet the rising demand for immunoglobulin therapies. Furthermore, Baxter International revealed its plans to increase operational efficiencies by automating certain plasma processing procedures earlier in September 2023.

    The market is also witnessing significant growth in valuation, driven by an increasing incidence of chronic diseases and an expanded patient population requiring plasma-derived therapies. Among recent strategic activities, in June 2023, Takeda Pharmaceutical finalized the acquisition of a biologics facility from Shire, enhancing its capabilities in the plasma sector.

    Moreover, CSL Behring launched new products targeting rare bleeding disorders, which contributed to a positive market outlook. The American Red Cross continues to play a vital role in plasma collection efforts, ensuring a steady supply for therapeutic needs. These activities indicate a robust and evolving market landscape in the U.S. Plasma Fractionation sector.

    Market Segmentation

    Plasma Fractionation Market End User Outlook

    • Hospitals
    • Ambulatory Surgical Centers
    • Blood Banks
    • Pharmaceutical Companies

    Plasma Fractionation Market Technology Outlook

    • Centrifugation
    • Chromatography
    • Precipitation
    • Filtration

    Plasma Fractionation Market Application Outlook

    • Neurology
    • Hematology
    • General Medicine
    • Immunology

    Plasma Fractionation Market Product Type Outlook

    • Immunoglobulin
    • Albumin
    • Coagulation Factors
    • Protease Inhibitors

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024 4.77(USD Billion)
    Market Size 2025 5.1(USD Billion)
    Market Size 2035 8.2(USD Billion)
    Compound Annual Growth Rate (CAGR) 4.412% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Cerus Corporation, Octapharma, Kedrion, Grifols, Sandoz, Takeda Pharmaceutical, Baxter International, CSL Behring, Shire, Emergent BioSolutions, Thermo Fisher Scientific, Pfizer, AbbVie, American Red Cross, BioMerieux
    Segments Covered Product Type, Application, End User, Technology
    Key Market Opportunities Increasing demand for immunoglobulins, Growing prevalence of chronic diseases, Advancements in separation technologies, Expanding applications in therapeutics, Rising awareness of plasma-derived therapies
    Key Market Dynamics Increasing demand for immunoglobulins, Growing prevalence of bleeding disorders, Advancements in fractionation technologies, Rising number of plasma collection centers, Stringent regulatory framework
    Countries Covered U.S.

    Market Highlights

    Author

    Rahul Gotadki
    Assistant Manager

    She holds an experience of about 6+ years in market research and business consulting, working under the spectrum of information communication technology, telecommunications and semiconductor domains. aarti conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. her expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc.

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    Latest Comments

    John Doe

    This is a great article! Really helped me understand the topic better.

    Posted on July 23, 2025, 10:15 AM
    Jane Smith

    Thanks for sharing this. I’ve bookmarked it for later reference.

    Posted on July 22, 2025, 7:45 PM

    FAQs

    What was the projected market size of the US Plasma Fractionation Market in 2024?

    The US Plasma Fractionation Market was expected to be valued at 5.1 USD Billion in 2024.

    How much is the US Plasma Fractionation Market expected to grow by 2035?

    By 2035, the US Plasma Fractionation Market is anticipated to reach a value of 8.2 USD Billion.

    What is the expected CAGR for the US Plasma Fractionation Market from 2025 to 2035?

    The expected CAGR for the US Plasma Fractionation Market is 4.412 percent from 2025 to 2035.

    What are the major product segments in the US Plasma Fractionation Market?

    The major product segments include Immunoglobulin, Albumin, Coagulation Factors, and Protease Inhibitors.

    What was the market size of Immunoglobulin in 2024?

    In 2024, the market size for Immunoglobulin was valued at 2.3 USD Billion.

    How much is the Albumin segment expected to be valued by 2035?

    The Albumin segment is projected to be valued at 2.5 USD Billion by 2035.

    Which companies are considered major players in the US Plasma Fractionation Market?

    Major players in the market include Cerus Corporation, Octapharma, Grifols, Baxter International, and CSL Behring.

    What is the market size for Coagulation Factors in 2035?

    The market size for Coagulation Factors is expected to reach 1.5 USD Billion by 2035.

    What are the key growth drivers for the US Plasma Fractionation Market?

    Key growth drivers include increasing demand for immunoglobulin therapies and advancements in medical technologies.

    How much is the Protease Inhibitors segment expected to grow by 2035?

    The Protease Inhibitors segment is anticipated to grow to 0.5 USD Billion by 2035.

    1. EXECUTIVE SUMMARY
    2. Market Overview
      1. Key Findings
      2. Market Segmentation
    3. Competitive Landscape
      1. Challenges and Opportunities
      2. Future Outlook
    4. MARKET INTRODUCTION
      1. Definition
      2. Scope of the study
        1. Research Objective
        2. Assumption
    5. Limitations
    6. RESEARCH METHODOLOGY
      1. Overview
      2. Data Mining
      3. Secondary Research
      4. Primary Research
        1. Primary Interviews
    7. and Information Gathering Process
      1. Breakdown of Primary Respondents
      2. Forecasting Model
      3. Market Size Estimation
        1. Bottom-Up
    8. Approach
      1. Top-Down Approach
      2. Data Triangulation
    9. Validation
    10. MARKET DYNAMICS
      1. Overview
    11. Drivers
      1. Restraints
      2. Opportunities
    12. MARKET FACTOR ANALYSIS
      1. Value chain Analysis
      2. Porter's Five Forces Analysis
    13. Bargaining Power of Suppliers
      1. Bargaining Power of Buyers
    14. Threat of New Entrants
      1. Threat of Substitutes
        1. Intensity
    15. of Rivalry
      1. COVID-19 Impact Analysis
        1. Market Impact Analysis
        2. Regional Impact
        3. Opportunity and Threat Analysis
    16. US PLASMA FRACTIONATION MARKET, BY PRODUCT TYPE (USD BILLION)
      1. Immunoglobulin
      2. Albumin
      3. Coagulation Factors
    17. Protease Inhibitors
    18. US PLASMA FRACTIONATION MARKET, BY APPLICATION (USD
    19. BILLION)
      1. Neurology
      2. Hematology
      3. General Medicine
      4. Immunology
    20. US PLASMA FRACTIONATION MARKET, BY END USER (USD
    21. BILLION)
      1. Hospitals
      2. Ambulatory Surgical Centers
    22. Blood Banks
      1. Pharmaceutical Companies
    23. US PLASMA FRACTIONATION
    24. MARKET, BY TECHNOLOGY (USD BILLION)
      1. Centrifugation
      2. Chromatography
      3. Precipitation
      4. Filtration
    25. COMPETITIVE LANDSCAPE
      1. Overview
      2. Competitive Analysis
      3. Market
    26. share Analysis
      1. Major Growth Strategy in the Plasma Fractionation Market
      2. Competitive Benchmarking
      3. Leading Players in Terms of Number
    27. of Developments in the Plasma Fractionation Market
      1. Key developments
    28. and growth strategies
      1. New Product Launch/Service Deployment
    29. Merger & Acquisitions
      1. Joint Ventures
      2. Major Players
    30. Financial Matrix
      1. Sales and Operating Income
        1. Major Players
    31. R&D Expenditure. 2023
    32. COMPANY PROFILES
      1. Cerus Corporation
        1. Financial Overview
        2. Products Offered
        3. Key
    33. Developments
      1. SWOT Analysis
        1. Key Strategies
    34. Octapharma
      1. Financial Overview
        1. Products Offered
    35. Key Developments
      1. SWOT Analysis
        1. Key Strategies
    36. Kedrion
      1. Financial Overview
        1. Products Offered
    37. Key Developments
      1. SWOT Analysis
        1. Key Strategies
    38. Grifols
      1. Financial Overview
        1. Products Offered
    39. Key Developments
      1. SWOT Analysis
        1. Key Strategies
    40. Sandoz
      1. Financial Overview
        1. Products Offered
    41. Key Developments
      1. SWOT Analysis
        1. Key Strategies
    42. Takeda Pharmaceutical
      1. Financial Overview
        1. Products Offered
        2. Key Developments
        3. SWOT Analysis
        4. Key Strategies
      2. Baxter International
        1. Financial Overview
    43. Products Offered
      1. Key Developments
        1. SWOT Analysis
        2. Key Strategies
      2. CSL Behring
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT
    44. Analysis
      1. Key Strategies
      2. Shire
        1. Financial
    45. Overview
      1. Products Offered
        1. Key Developments
    46. SWOT Analysis
      1. Key Strategies
      2. Emergent BioSolutions
        1. Financial Overview
        2. Products Offered
        3. Key
    47. Developments
      1. SWOT Analysis
        1. Key Strategies
    48. Thermo Fisher Scientific
      1. Financial Overview
        1. Products
    49. Offered
      1. Key Developments
        1. SWOT Analysis
    50. Key Strategies
      1. Pfizer
        1. Financial Overview
    51. Products Offered
      1. Key Developments
        1. SWOT Analysis
        2. Key Strategies
      2. AbbVie
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT
    52. Analysis
      1. Key Strategies
      2. American Red Cross
    53. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. BioMerieux
        1. Financial Overview
        2. Products Offered
    54. Key Developments
      1. SWOT Analysis
        1. Key Strategies
    55. APPENDIX
      1. References
      2. Related Reports
    56. MARKET SIZE ESTIMATES & FORECAST, BY PRODUCT TYPE, 2019-2035 (USD BILLIONS)
    57. APPLICATION, 2019-2035 (USD BILLIONS)
    58. SIZE ESTIMATES & FORECAST, BY END USER, 2019-2035 (USD BILLIONS)
    59. US PLASMA FRACTIONATION MARKET SIZE ESTIMATES & FORECAST, BY TECHNOLOGY,
    60. 2035 (USD BILLIONS)
    61. MARKET SYNOPSIS
    62. TYPE
    63. US PLASMA FRACTIONATION MARKET ANALYSIS BY TECHNOLOGY
    64. CRITERIA OF PLASMA FRACTIONATION MARKET
    65. IMPACT ANALYSIS: PLASMA FRACTIONATION MARKET
    66. ANALYSIS: PLASMA FRACTIONATION MARKET
    67. FRACTIONATION MARKET
    68. (% SHARE)
    69. TO 2035 (USD Billions)
    70. (% SHARE)
    71. TO 2035 (USD Billions)
    72. (% SHARE)
    73. (USD Billions)
    74. (% SHARE)
    75. TO 2035 (USD Billions)

    US Plasma Fractionation Market Segmentation

    • Plasma Fractionation Market By Product Type (USD Billion, 2019-2035)

      • Immunoglobulin
      • Albumin
      • Coagulation Factors
      • Protease Inhibitors

    • Plasma Fractionation Market By Application (USD Billion, 2019-2035)

      • Neurology
      • Hematology
      • General Medicine
      • Immunology

    • Plasma Fractionation Market By End User (USD Billion, 2019-2035)

      • Hospitals
      • Ambulatory Surgical Centers
      • Blood Banks
      • Pharmaceutical Companies

    • Plasma Fractionation Market By Technology (USD Billion, 2019-2035)

      • Centrifugation
      • Chromatography
      • Precipitation
      • Filtration
    Infographic

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