Vanishing Bone Disease Market Size was valued at USD 2.00 Billion in 2023. The Vanishing Bone Disease industry is projected to grow from USD 3.20 Billion in 2024 to USD 4.50 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.80% during the forecast period (2024 - 2032).
Vanishing bone disease or Gorham-stout syndrome is a rare skeletal disease characterized by progressive osteolysis and the proliferation of lymphatic vessels within the bone which leads to the destruction and absorption of bone. Additionally, the bones affected by the disease are more prone to osteopenia and fracture. Furthermore, the exact cause of the disease is unknown. However, it is considered to be caused due to the improper development of the lymphatic system.
According to the National Center for Advancing Translational Sciences (NIH), in 2016, the number of cases of vanishing bone disease reported ranged from 64 to 200 cases globally. The growing occurrence of the disease is the key driver for the growth of the market. Furthermore, current research for the development of an effective therapeutic intervention for disease treatment is expected to contribute to the growth of the market.
However, lack of awareness of the disease in developing economies, high treatment cost restrains the market growth. Furthermore, challenges in diagnosis of the disease in the patient pool may hamper the growth of the market.
The global vanishing bone disease market is segmented on the basis of the diagnosis, treatment, and end-user.
On the basis of diagnosis, the market is classified as X-rays, CT scans, MRIs, ultrasound, nuclear medicine, and others.
On the basis of treatment, the market is segmented as medical therapy and radiation therapy. The medicine therapy is segmented into bisphosphonates, vitamin D, interferon, a-2b interferon, calcium, adrenal extracts, androgen, bleomycin, and others. The radiation therapy is further segmented into chest drainage, thoracic duct ligation, pleurodesis, pleurectomy, and others.
On the basis of end-user, the global market is segmented as hospitals & clinics, diagnostic centers, ambulatory surgical centers, and others.
Geographically, the market has been segmented into America, Europe, Asia Pacific, and the Middle East and Africa. The American market is further segmented into North America and South America. North America is further classified as the U.S. and Canada.
The European market is segmented into Western Europe and Eastern Europe. Western Europe is further classified as Germany, France, the U.K., Italy, Spain, and the rest of Western Europe.
The Asia Pacific market is segmented into Japan, China, India, Republic of Korea, Australia, and the rest of Asia Pacific.
The Middle Eastern and African market is segmented into the Middle East and Africa.
The global vanishing bone disease market consists of four regions: Americas, Europe, Asia Pacific and the Middle East & Africa. The North American region dominates the global vanishing bone market due to the existing well-established healthcare system, increasing occurrences of rare diseases. For instance, according to the National Institute of Health, rare disorders that affect approximately 30 million people in the United States. Furthermore, according to the U.S. FDA, rare diseases or disorder affects an approximate 200,000 people in the United States.
Europe holds the second market share in the vanishing bone disease market. It is expected that the government support towards research & development expenditure and rising incidences of rare diseases is likely to drive the European market. For instance, according to the European Commission, rare diseases comprises 5000 to 8000 life-threatening or chronically debilitating diseases which together affect from 27 and 36 million people in the European Union.
The Asia Pacific, vanishing bone disease market, consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia Pacific. The vanishing bone disease market growth in this region is driven by rising healthcare expenditure, rising occurrences of rare diseases, and growing bone disorders, technological advancements in interventional radiology segment. For instance, in February 2018, Elekta AB received clearance from China Food and Drug Administration (CFDA) for its Leksell Gamma Knife Icon radiosurgery system.
The Middle East & Africa holds the lowest share of the global vanishing bone disease market due to lack of awareness of rare diseases, the low incidence rate of the disease and poor medical facilities, especially in the African region.
Varian Medical Systems, Inc
Elekta AB
C. R. Bard, Inc
Teleflex Incorporated
Vygon S.A
Medtronic plc
Cook Medical
Smiths Medical
ATMOS MedizinTechnik GmbH & Co. KG
Merck & Co
Sanofi-Aventis
F. Hoffmann-La Roche AG
Novartis International AG
Market Research Future research is conducted by industry experts who offer insight into industry structure, market segmentation, Treatment assessment, competitive landscape (CL), penetration, as well as on emerging trends. Besides primary interviews (~ 80%) and secondary research (~ 20%), their analysis is based on their years of professional expertise in respective industries. Our analysts also predict where the market will be headed in the next five to ten years, by analyzing historical trends and current market positions. Furthermore, the varying trends of segments & categories geographically presented are studied and are estimated based on primary & secondary research.
Extensive primary research was conducted to gain a deeper insight into the market and the industry performance. In this particular report, we have conducted primary surveys (interviews) with the key level executives (VPs, CEOs, Marketing Directors, Business Development Managers, and many more) of the major players who are active in the market. In addition to analyzing the current and historical trends, our analysts predict where the market is headed, over the next five to ten years.
Secondary research was mainly used to collect and identify information useful for an extensive, technical, market-oriented, and commercial study of the vanishing bone disease market. It was also used to obtain key information about major players, market classification and segmentation according to the industry trends, geographical markets, & developments related to the market and Treatment Perspectives. For this study, analysts have gathered information from various credible sources, such as annual reports, SEC filings, journals, white papers, corporate presentations, company websites, the international organization of chemical manufacturers, some paid databases and many others.
Global Vanishing Bone Disease Market, by Diagnosis
X-rays
CT Scans
MRIs
Ultrasound
Nuclear Medicine
Others
Global Vanishing Bone Disease Market, by Treatment
Medicine Therapy
Bisphosphonates
Vitamin D
Interferon
a-2b Interferon
Calcium
Adrenal extracts
Androgens
Bleomycin
Others
Radiation Therapy
Chest drainage
Thoracic Duct Ligation
Pleurodesis
Pleurectomy
Others
Global Vanishing Bone Disease Market, by End-User
Hospitals and clinics
Diagnostic centers
Ambulatory surgical centers
Global Vanishing Bone Disease Market, by Region
Americas
North America
U.S.
Canada
South America
Europe
Western Europe
Germany
France
Italy
Spain
U.K.
Rest of Western Europe
Eastern Europe
Asia Pacific
Japan
China
India
Australia
Republic of Korea
Rest of Asia Pacific
The Middle East & Africa
Middle East
Africa
Intended Audience
Pharmaceutical Companies
Research and Development (R&D) Companies
Government Research Institutes
| Report Attribute/Metric | Details |
| Market Size | 4.50 Billion 2032 |
| CAGR | 7.80% |
| Base Year | 2023 |
| Forecast Period | 2024-2032 |
| Historical Data | 2021 |
| Forecast Units | Value (USD Billion) |
| Report Coverage | Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
| Segments Covered | Diagnosis, Treatment, and End-user |
| Geographies Covered | North America, Europe, Asia-Pacific, and Rest of the World (RoW) |
| Key Vendors | Varian Medical Systems, Inc., Elekta AB, C. R. Bard, Inc., Teleflex Incorporated, Vygon S.A. Medtronic plc., Cook Medical, Smiths Medical, ATMOS MedizinTechnik GmbH & Co. KG, Merck & Co., Sanofi-Aventis, F. Hoffmann-La Roche AG, and Novartis International AG |
| Key Market Opportunities | Research for the development of the effective therapeutic intervention for the disease treatment |
| Key Market Drivers | Number of cases of vanishing bone disease Growing occurrence of the disease |
Frequently Asked Questions (FAQ) :
VANISHING BONE DISEASE or Gorham-stout syndrome is a rare skeletal disease characterized by progressive osteolysis and proliferation of lymphatic vessels within the bone, which leads to the destruction and absorption of bone.
Global Vanishing Bone Disease Market is expected to exhibit a strong 7.80% CAGR over the forecast period from 2024-2032.
The growing prevalence of vanishing bone disease is the major driver for the market.
North America dominates the Global Vanishing Bone Disease Market.
Leading players in the Vanishing Bone Disease Market include Elekta AB, Varian Medical Systems, and Teleflex Inc., among others.
Assistant Manager He holds an experience of about 7+ years in market research and business consulting, working under the spectrum of life sciences and healthcare domains. rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. his expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. in addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives
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