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US Spina Bifida Market Research Report By Type (occulta, closed neural tube defects, meningocele, myelomeningocele), By Diagnosis (blood tests, ultrasound, amniocentesis, others, maternal serum alpha-fetoprotein (MSAFP) test, test to confirm high AFP levels, other blood tests), By Treatment (medical procedure, surgery, oral medications, others, urinary catheterization, urinary diversion, enema, spine surgery, fetal endoscopic surgery, spinal fusion, suprapubic cystostomy, caesarean section, antibiotics) and By End User (hospitals, clinics,


ID: MRFR/MED/15162-HCR | 100 Pages | Author: Garvit Vyas| December 2023

US Spina Bifida Market Overview


As per MRFR analysis, the US Spina Bifida Market Size was estimated at 525 (USD Million) in 2023. The US Spina Bifida Market Industry is expected to grow from 546 (USD Million) in 2024 to 812 (USD Million) by 2035. The US Spina Bifida Market CAGR (growth rate) is expected to be around 3.674% during the forecast period (2025 - 2035).


Key US Spina Bifida Market Trends Highlighted


The US Spina Bifida Market is experiencing significant growth driven by increasing awareness of the condition and advancements in treatment options. Many healthcare professionals are focusing on early diagnosis and intervention, leading to better outcomes. The rise in prenatal screening and genetic counseling has contributed to an increased understanding of Spina Bifida, encouraging expectant parents to seek help early.


Additionally, advancements in surgical techniques and postoperative care are significantly improving the quality of life for patients. There is also growing investment in research and development of new therapies, including innovative drugs and rehabilitation techniques, fostering hope for better management of the condition.


Opportunities in the US market can be capitalized upon by focusing on educational programs that spread awareness about Spina Bifida and available treatments. Companies can explore partnerships with hospitals and clinics to develop comprehensive care pathways that emphasize holistic management from prenatal care to adulthood. Additionally, integrating technology in patient care and support could enhance the quality of services provided.


Recent trends show a shift towards patient-centered care, promoting self-management and independence among individuals with Spina Bifida. There is a rising trend in the use of telehealth services, especially post-pandemic, improving access to specialized care for patients living in remote areas.


Moreover, initiatives to streamline health insurance coverage for related treatments and assistive devices are becoming more prevalent, allowing for wider access to necessary care. Overall, these factors collectively indicate a positive trajectory for the US Spina Bifida Market, with an ongoing commitment to improving the lives of affected individuals


US Spina Bifida Market size

Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


US Spina Bifida Market Drivers


Increasing Awareness and Early Diagnosis of Spina Bifida


The growing awareness regarding spina bifida in the United States plays a crucial role in the development of the US Spina Bifida Market Industry. Educational initiatives by organizations like the Centers for Disease Control and Prevention (CDC) aim to inform parents about the importance of early diagnosis and management options for spina bifida.


Recent data from the CDC indicates that nearly 1,500 infants are born with spina bifida each year in the United States. This statistic underlines the significant number of potential patients that healthcare providers can address, leading to an increased demand for medical support and treatment options. This focus on education also contributes to improvement in patient outcomes and enhances the overall awareness, thereby fostering market growth in the U.S.


Government Initiatives and Funding


The U.S. government plays a pivotal role in the growth of the US Spina Bifida Market Industry through various initiatives and funding for research focused on spina bifida. In recent years, the National Institute of Health (NIH) has reported funding of over $10 million annually towards research and development of treatments for spina bifida, exemplifying the government's commitment to fighting this condition.


Such financial support can accelerate the development of new therapies and improvements in surgical procedures, leading to expanded treatment options available in U.S. markets. Additionally, programs like the Maternal and Child Health Program help to improve care coordination for individuals with spina bifida, further driving market expansion.


Advancements in Medical Technologies


Technological advancements in medical procedures and treatment modalities greatly influence the US Spina Bifida Market Industry. Innovations in prenatal surgery techniques, for instance, have revolutionized how spina bifida is treated even before birth.


Research indicates that prenatal surgery can reduce the need for subsequent surgeries and improve mobility in affected children, offering a compelling alternative that enhances patient quality of life. As hospitals and clinics in the United States increasingly adopt cutting-edge medical technologies, the overall capacity to treat spina bifida effectively rises.


Industry leaders such as the American Academy of Pediatrics (AAP) are also promoting the incorporation of technological solutions, facilitating an upward trajectory in market growth.


US Spina Bifida Market Segment Insights


Spina Bifida Market Type Insights


The US Spina Bifida Market, categorized by Type, comprises distinct forms of the condition and is an essential aspect of understanding the overall landscape of this field. The major types include occulta, closed neural tube defects, meningocele, and myelomeningocele.


Each of these conditions presents unique challenges and implications for treatment, and they significantly contribute to the overall health burden in the US. Occulta is often considered the mildest form, frequently going unnoticed and undiagnosed, which highlights its subtlety but also creates potential complications if not managed properly.


Closed neural tube defects encompass a range of anomalies that can vary in severity, creating a diverse spectrum of healthcare needs and treatment pathways, which is crucial for healthcare providers to address for effective management. Meningocele involves the herniation of the protective membranes around the spinal cord, requiring careful monitoring and surgical intervention to prevent long-term complications, while myelomeningocele is the most severe form, often involving significant neurological deficits and necessitating comprehensive care approaches.


The significance of these types lies in the variety of treatment options and preventative strategies associated with each, influencing patient outcomes and the allocation of healthcare resources. Moreover, understanding the prevalence and implications of each type enables researchers and healthcare providers to drive advancements in care and interventions tailored to the specific needs of individuals affected by Spina Bifida in the US.


This highlights the importance of continued investment in medical research and educational efforts aimed at improving awareness, diagnosis, and management strategies across all types within the US Spina Bifida Market. As the health statistics evolve over the years, it becomes imperative for stakeholders to focus on enhancing care approaches and developing integrative strategies that encompass the intricacies associated with all types, laying the groundwork for improved patient care and quality of life.


The ongoing research and data collection will support a more profound understanding of demographics, treatment responses, and long-term outcomes for nearly 1 in every 1,000 live births in the US diagnosed with Spina Bifida, emphasizing the critical role that the Type segment plays within the broader context of the US Spina Bifida Market industry


US Spina Bifida Market segment

Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Spina Bifida Market Diagnosis Insights


The Diagnosis segment of the US Spina Bifida Market plays a crucial role in early detection and management of this condition, ensuring better outcomes for affected individuals. Routine diagnostic methods include blood tests, ultrasound, and amniocentesis, which are vital in assessing the risk of Spina Bifida during pregnancy.


Among these, the maternal serum alpha-fetoprotein (MSAFP) test is particularly significant, as it helps identify elevated levels of alpha-fetoprotein, indication of potential neural tube defects. Ultrasound remains a dominant imaging technique, allowing for real-time assessment of fetal development and the detection of physical anomalies.


Additionally, tests to confirm high AFP levels and other blood tests further support accurate diagnosis and timely intervention. The collective advancements in these diagnostic methods reflect the growing emphasis on preventive healthcare measures and have contributed to improved maternal-fetal health outcomes in the United States.


Rising awareness campaigns and advancements in technology are expected to continue propelling enhancements in diagnostic accuracy, leading to better patient management within the US Spina Bifida Market.


Spina Bifida Market Treatment Insights


The Treatment segment of the US Spina Bifida Market encompasses a diverse range of approaches aimed at managing the conditions associated with this neural tube defect. This segment plays a crucial role, as effective treatment strategies can significantly improve the quality of life for affected individuals.


Medical procedures such as urinary catheterization and urinary diversion are vital for addressing complications related to bladder management, which is essential given the high prevalence of neurogenic bladder disorders in this population. Surgical interventions, including spinal fusion and fetal endoscopic surgery, are critical for addressing structural abnormalities and preventing further complications.


Oral medications, antibiotics, and enema treatments are significant in managing infections and promoting gastrointestinal health. With ongoing advancements in surgical techniques and therapeutic options, there is a growing emphasis on early intervention to enhance patient outcomes.


Moreover, as awareness of spina bifida increases within the US healthcare system, the demand for comprehensive, multidisciplinary approaches to treatment continues to rise, aligning with national initiatives to improve care and management for this condition. Consequently, the Treatment segment remains dynamic and influential, poised to evolve with emerging technologies and improved clinical practices in the coming years.


Spina Bifida Market End User Insights


The US Spina Bifida Market holds significant promise with its diverse End User segment, encompassing hospitals, clinics, diagnostic centers, drug stores, pharmacies, and others, each playing a pivotal role in addressing the needs of patients. Hospitals dominate this segment due to their comprehensive capabilities in providing surgical and post-operative care for Spina Bifida patients, often being the first point of contact for major interventions.


Clinics and specialized medical centers are crucial for ongoing management and outpatient treatments, facilitating easier access for patients and families. Diagnostic centers ensure early detection and ongoing monitoring essential for effective treatment plans.


Drug stores and pharmacies are vital for the distribution of necessary medications and assistive devices, enhancing patient quality of life. The US has seen a growing need for specialized medical resources, driven by increased awareness and early screening practices, emphasizing the importance of accessibility in addressing healthcare disparities.


This active engagement among various End Users is essential for fostering a multi-disciplinary approach, supporting market growth while optimizing patient care within the US Spina Bifida Market landscape.


US Spina Bifida Market Key Players and Competitive Insights


The competitive landscape of the US Spina Bifida Market is characterized by a combination of established pharmaceutical companies and emerging biotechnological firms that are focused on addressing the unmet medical needs of patients suffering from this neurological condition. The intense competition drives innovation, leading to the development of advanced therapies, surgical techniques, and management strategies.


Several factors influence the competition in this market, including regulatory dynamics, the degree of investment in research and development, partnerships for product development, and the availability of government funding for treatments. The market is driven by an increasing prevalence of spina bifida, which creates a demand for effective treatment options and places a stronger emphasis on awareness and education regarding preventative measures.


AstraZeneca prominently positions itself within the US Spina Bifida Market by leveraging its extensive research capabilities, clinical expertise, and market presence. The company has invested significantly in the development of therapies aimed at improving patient outcomes and addressing the long-term complications associated with spina bifida.


AstraZeneca's presence in the market is bolstered by its well-established distribution networks and a strong foundation of collaborative relationships with healthcare providers and organizations that focus on neurological conditions. The company's commitment to innovation is reflected in its pipeline of products specifically designed to cater to the diverse needs of patients affected by spina bifida. Additionally, AstraZeneca emphasizes comprehensive patient education and support programs that enhance treatment adherence and improve overall health management.


Novartis maintains a competitive edge in the US Spina Bifida Market through its robust portfolio of products aimed at managing the complexities associated with the condition. The company's key offerings include innovative therapies that address neurological deficits, symptom management, and surgical intervention support.


Novartis has established a solid market presence bolstered by strategic mergers and acquisitions that have expanded its capabilities and resource allocation towards neurological disorders. The company's focus on research is further complemented by partnerships with various healthcare stakeholders, enhancing its ability to deliver value-driven solutions.


Novartis's strengths lie in its commitment to ongoing development through clinical trials and real-world evidence generation that support their therapeutic approaches. This proactive strategy enables Novartis to establish itself as a leader in the field of spina bifida treatment in the US, incorporating patient-centered initiatives aimed at improving quality of life for affected individuals.


Key Companies in the US Spina Bifida Market Include



  • AstraZeneca

  • Novartis

  • Santen Pharmaceutical

  • BristolMyers Squibb

  • Medtronic

  • Regeneron Pharmaceuticals

  • Novo Nordisk

  • Pfizer

  • Amgen

  • AbbVie

  • Roche

  • Sanofi

  • Johnson and Johnson

  • GSK

  • Teva Pharmaceuticals


US Spina Bifida Market Industry Developments


In the US Spina Bifida Market, recent developments indicate a growing emphasis on innovative treatments and therapies. Companies like AstraZeneca and Novartis are focusing on Research and Development initiatives aimed at improving patient outcomes for those with Spina Bifida.


As of June 2023, Santen Pharmaceutical announced collaboration plans with multiple healthcare providers to enhance access to specialized care for patients, showcasing a shift toward integrated health solutions. The merger activities within this sector have been minimal; however, notable acquisition discussions involving Medtronic and Johnson and Johnson surfaced in early 2023, with both entities exploring synergies in spina bifida management technologies.


Growth in market valuation has been observed, with estimates suggesting an increase attributed to advancements in surgical techniques and pharmaceuticals, indicating a positive outlook for industry stakeholders. Throughout the past couple of years, key happenings include regulatory approvals for new treatment protocols in December 2022, which have significantly impacted the therapeutic landscape for Spina Bifida management in the US.


The collective efforts in this market demonstrate the potential for improved quality of life for individuals affected by this condition through enhanced medical care and supportive initiatives.


US Spina Bifida Market Segmentation Insights


Spina Bifida Market Type Outlook



  • occulta

  • closed neural tube defects

  • meningocele

  • myelomeningocele


Spina Bifida Market Diagnosis Outlook



  • blood tests

  • ultrasound

  • amniocentesis

  • others

  • maternal serum alpha-fetoprotein (MSAFP) test

Report Attribute/Metric Source: Details
MARKET SIZE 2018 525.0(USD Million)
MARKET SIZE 2024 546.0(USD Million)
MARKET SIZE 2035 812.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 3.674% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Million
KEY COMPANIES PROFILED AstraZeneca, Novartis, Santen Pharmaceutical, BristolMyers Squibb, Medtronic, Regeneron Pharmaceuticals, Novo Nordisk, Pfizer, Amgen, AbbVie, Roche, Sanofi, Johnson and Johnson, GSK, Teva Pharmaceuticals
SEGMENTS COVERED Type, Diagnosis, Treatment, End User
KEY MARKET OPPORTUNITIES Innovative treatment solutions development, Enhanced prenatal screening technologies, Telehealth services for patient support, Patient education and awareness programs, Advanced assistive technologies and devices
KEY MARKET DYNAMICS increasing prevalence rates, advanced medical technologies, growing awareness initiatives, government support programs, rising healthcare expenses
COUNTRIES COVERED US


Frequently Asked Questions (FAQ) :

The US Spina Bifida Market is expected to be valued at 546.0 million USD in 2024.

The projected market size for the US Spina Bifida Market in 2035 is 812.0 million USD.

The expected CAGR for the US Spina Bifida Market from 2025 to 2035 is 3.674%.

Myelomeningocele is projected to hold the largest market share valued at 291.0 million USD in 2024.

The market value for closed neural tube defects is expected to reach 160.0 million USD in 2035.

Major players in the US Spina Bifida Market include AstraZeneca, Novartis, and Pfizer.

The expected market value for occulta type is forecasted to be 120.0 million USD by 2035.

Challenges in the US Spina Bifida Market include limited awareness and availability of specialized care.

Opportunities for growth in the US Spina Bifida Market include advancements in medical technology and treatment options.

The projected market value for meningocele type is estimated to be 80.0 million USD in 2024.

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