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    US Non Invasive Prenatal Testing Market

    ID: MRFR/HC/17927-HCR
    100 Pages
    Garvit Vyas
    September 2025

    US Non-Invasive Prenatal Testing Market Research Report By Test Type (Cell-Free DNA Testing, Biochemical Testing, Combined Screening), By Application (Fetal Gender Determination, Chromosomal Abnormalities Screening, Rhesus Disease Screening), By Technology (Next Generation Sequencing, Microarray Analysis, Polymerase Chain Reaction) and By End User (Hospitals, Diagnostic Laboratories, Direct-to-Consumer Companies) - Forecast to 2035

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    Table of Contents

    US Non Invasive Prenatal Testing Market Summary

    The US Non-Invasive Prenatal Testing market is projected to grow significantly from 539 USD Million in 2024 to 1326 USD Million by 2035.

    Key Market Trends & Highlights

    US Non-Invasive Prenatal Testing Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 8.53 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 1326 USD Million, indicating robust growth potential.
    • In 2024, the market is valued at 539 USD Million, reflecting a strong foundation for future expansion.
    • Growing adoption of non-invasive prenatal testing due to increasing awareness of prenatal health is a major market driver.

    Market Size & Forecast

    2024 Market Size 539 (USD Million)
    2035 Market Size 1326 (USD Million)
    CAGR (2025-2035) 8.53%

    Major Players

    Illumina, LabCorp, Fulgent Genetics, Sequenom, Myriad Genetics, Bionano Genomics, Genetic Technologies, PerkinElmer, Sema4, Horizon Genomics, Quest Diagnostics, Roche, Cleveland HeartLab, Invitae, Natera

    US Non Invasive Prenatal Testing Market Trends

    The US Non-Invasive Prenatal Testing (NIPT) market is experiencing notable trends driven by several key factors. A significant driver in this market is the increasing awareness among expectant parents about prenatal screening options because of the rise in maternal age and the associated risks of genetic disorders. This heightened awareness has led to a growing acceptance of NIPT as a standard part of prenatal care. Furthermore, advancements in technology have improved the accuracy and efficiency of NIPT, making it a preferred choice for many healthcare providers and patients alike.

    Opportunities to be explored in this landscape include the potential for expanding NIPT applications beyond traditional screenings for Down syndrome and other chromosomal abnormalities to include a broader range of genetic conditions, providing a more comprehensive assessment at an earlier stage in pregnancy. Recent trends show that there is a shift towards more personalized medicine, where NIPT is being integrated into routine prenatal care protocols, thereby making it more accessible to a larger segment of the population.

    Additionally, the increase in online health platforms has facilitated easier communications between healthcare providers and patients, enhancing patient access to NIPT information and services.

    The rise of telehealth services also offers a new channel for women to gain insight into non-invasive screening, promoting wider adoption of these tests. Moreover, ongoing research and clinical trials are expected to yield new insights and applications for NIPT, further driving innovation in this field. Overall, the US Non-Invasive Prenatal Testing market is poised for growth driven by technological advancements, increased consumer awareness, and expanded applications of testing.

    US Non Invasive Prenatal Testing Market Drivers

    Market Segment Insights

    Non-Invasive Prenatal Testing Market Test Type Insights

    The US Non-Invasive Prenatal Testing Market is characterized by its diverse Test Type categories, which cater to varying needs in prenatal care. Among these, Cell-Free DNA testing has gained substantial traction due to its high accuracy and reliability in identifying chromosomal abnormalities. This test analyzes small fragments of fetal DNA present in the maternal blood, making it a preferred option for early detection without posing risks to the fetus.

    The demand for this type of testing has been bolstered by rising awareness regarding prenatal health and advancements in Genetic Testing technology, aligning with public health objectives to improve maternal and child health outcomes in the US.

    Another significant category is Biochemical Testing, which plays a crucial role in assessing maternal serum markers to evaluate the risk of fetal anomalies. This approach combines various biomarkers to provide a comprehensive assessment of fetal health, making it an important tool for clinicians. While it may not offer the same accuracy as Cell-Free DNA testing, it remains relevant for its cost-effectiveness and accessibility, particularly for populations with limited access to more advanced testing options.

    Combined Screening represents an integrated approach that incorporates both maternal blood tests and ultrasound assessments to provide a more holistic view of fetal health. This multi-faceted strategy enhances the effectiveness of prenatal screenings by identifying potential risks for conditions like Down syndrome in early gestation periods. The growth of this category benefits from a steady demand for thorough prenatal evaluations, reflecting the emphasis on proactive healthcare decisions among expectant parents in the US.

    Collectively, these Test Types within the US Non-Invasive Prenatal Testing Market showcase a growing trend towards personalized medicine and preventive care. As healthcare providers and expectant parents increasingly recognize the importance of early screening and risk assessment, these test categories are likely to experience heightened adoption, driven by both technological innovations and a commitment to enhancing prenatal healthcare quality. In this evolving landscape, the selection of appropriate testing methodologies will be pivotal for healthcare professionals in providing optimal care to patients, ensuring they make informed decisions regarding their prenatal health.

    Non-Invasive Prenatal Testing Market Application Insights

    The US Non-Invasive Prenatal Testing Market is characterized by its diverse applications, which play a crucial role in modern prenatal care. Within this segment, Fetal Gender Determination has gained significant traction, as expectant parents seek early knowledge of their baby's gender for planning and personal preference. Chromosomal Abnormalities Screening is another vital application, aiding in the early detection of conditions such as Down syndrome, thereby influencing decision-making for families and healthcare providers. Rhesus Disease Screening is critical for identifying Rh incompatibility, which can lead to serious complications in pregnancies.

    This application not only enhances maternal-fetal health outcomes but also significantly contributes to effective prenatal management strategies. The ongoing advancements in testing technologies and increased awareness among healthcare professionals about the benefits and reliability of these non-invasive methods contribute to market growth. Overall, the focus on these applications underscores the importance of informed prenatal care in the US, aligning with the broader trend of personalized medicine.

    Non-Invasive Prenatal Testing Market Technology Insights

    The Technology segment of the US Non-Invasive Prenatal Testing Market encompasses advanced methodologies that significantly enhance prenatal screening processes. Among these, Next Generation Sequencing (NGS) stands out for its ability to provide high-resolution genomic information, allowing for a comprehensive understanding of fetal conditions. This technology's increasing adoption is driven by its accuracy and depth of analysis compared to traditional methods. Microarray Analysis offers another essential tool by facilitating the detection of chromosomal abnormalities, making it vital for identifying genetic disorders early in pregnancy.

    Additionally, Polymerase Chain Reaction (PCR) technology, known for its rapid detection capabilities, plays a crucial role in diagnosing various conditions, elevating its importance in prenatal diagnostics. The synergy of these technologies not only improves testing precision but also enhances the overall trust in non-invasive prenatal testing, reflecting the growing demand for reliable and efficient maternity care solutions in the US. As healthcare providers and patients continue to embrace these innovations, the Technology segment is positioned to lead significant advancements in prenatal care.

    Non-Invasive Prenatal Testing Market End User Insights

    The End User segment of the US Non-Invasive Prenatal Testing Market is a vital area characterized by several key participants, which include hospitals, diagnostic laboratories, and direct-to-consumer companies. Hospitals play a significant role as they provide comprehensive prenatal care and typically have the resources and trained professionals necessary for administering these tests. Diagnostic laboratories are crucial for performing the actual analyses and generating reliable results, thus contributing to the overall efficiency of prenatal screening.

    Furthermore, direct-to-consumer companies have gained prominence by allowing prospective parents to access testing services conveniently from home, catering to a growing demand for personalized healthcare solutions. The integration of advanced technologies and increasing awareness about prenatal health are driving trends across these segments. Moreover, the rising incidence of genetic disorders and the preference for non-invasive testing methods present substantial opportunities for growth. As healthcare policies evolve and consumer attitudes shift towards proactive healthcare management, each of these segments is positioned to capitalize on the expanding US Non-Invasive Prenatal Testing Market revenue dynamics.

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    Regional Insights

    Key Players and Competitive Insights

    The US Non-Invasive Prenatal Testing Market is characterized by a dynamic landscape where various companies vie for positioning through innovation, strategic partnerships, and technological advancements. This market segment has gained significant traction owing to its potential to provide expectant parents with critical information regarding fetal health without the risks associated with invasive procedures. Key players are adopting various strategies, such as expanding their product portfolios and enhancing the accuracy and reliability of their testing solutions. Additionally, the regulatory environment and reimbursement policies significantly influence the competitive dynamics within this market.

    Companies are focusing on building strong relationships with healthcare providers, streamlining their operations, and expanding their market reach to gain a competitive edge and improve patient accessibility to non-invasive prenatal testing solutions.

    Illumina

    Illumina has established itself as a pioneer in the US Non-Invasive Prenatal Testing Market, leveraging its advanced sequencing technology to offer high-precision genetic testing solutions. The company is renowned for its cutting-edge platforms that drive innovation in prenatal testing, which has significantly improved the detection rates for various genetic conditions. Illumina’s strong presence in the market is bolstered by its commitment to research and development, allowing it to remain at the forefront of technological advancements in prenatal diagnostics. In addition to their superior test accuracy and reliability, the company also benefits from strong relationships with healthcare providers and institutions.

    This reputation, combined with a robust portfolio of products for both prenatal and genetic testing, positions Illumina as a formidable player in this competitive landscape.

    LabCorp

    LabCorp is a leading entity in the US Non-Invasive Prenatal Testing Market, recognized for offering a range of advanced diagnostic solutions tailored to prenatal care. The company provides key products and services that include comprehensive genetic testing and personalized prenatal screening options, which cater to diverse needs in maternal-fetal medicine. LabCorp's strengths lie in its extensive network of laboratories and a solid foundation of scientific and technical expertise, which enable it to maintain high standards of quality and efficiency in its testing processes.

    The company has actively pursued mergers and acquisitions to bolster its capabilities and expand its service offerings, thereby enhancing its market presence. Through these strategic moves, LabCorp aims to innovate continuously in the prenatal testing arena, providing healthcare providers and patients with reliable insights into fetal health and wellbeing.

    Key Companies in the US Non Invasive Prenatal Testing Market market include

    Industry Developments

    The US Non-Invasive Prenatal Testing Market has seen significant developments recently, particularly involving leading companies such as Illumina, LabCorp, and Myriad Genetics. A notable trend includes the increasing acceptance and integration of non-invasive prenatal testing technologies within clinical practice, as healthcare providers acknowledge their benefits in early detection of genetic disorders. In September 2023, Natera emphasized growth in market valuation driven by expanded test portfolios and enhanced accuracy rates, contributing to a widening adoption among expectant parents.

    Mergers and acquisitions have also shaped the market landscape; for instance, in July 2023, Illumina acquired a smaller player to bolster its NIPT offerings, enhancing its competitiveness in the segment. The past few years have marked critical milestones, such as introduction of new tests by Sequenom and LabCorp in 2021 that have paved the way for broader access and lower costs for consumers. The growing trend towards personalized medicine and advancements in genomic technologies continues to redefine the industry's trajectory, as stakeholders prepare for an evolving regulatory framework and increased demand for innovative solutions in prenatal care.

    Market Segmentation

    Non-Invasive Prenatal Testing Market End User Outlook

    • Hospitals
    • Diagnostic Laboratories
    • Direct-to-Consumer Companies

    Non-Invasive Prenatal Testing Market Test Type Outlook

    • Cell-Free DNA Testing
    • Biochemical Testing
    • Combined Screening

    Non-Invasive Prenatal Testing Market Technology Outlook

    • Next Generation Sequencing
    • Microarray Analysis
    • Polymerase Chain Reaction

    Non-Invasive Prenatal Testing Market Application Outlook

    • Fetal Gender Determination
    • Chromosomal Abnormalities Screening
    • Rhesus Disease Screening

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2018 494.9(USD Million)
    MARKET SIZE 2024 539.0(USD Million)
    MARKET SIZE 2035 1326.0(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 8.528% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Million
    KEY COMPANIES PROFILED Illumina, LabCorp, Fulgent Genetics, Sequenom, Myriad Genetics, Bionano Genomics, Genetic Technologies, PerkinElmer, Sema4, Horizon Genomics, Quest Diagnostics, Roche, Cleveland HeartLab, Invitae, Natera
    SEGMENTS COVERED Test Type, Application, Technology, End User
    KEY MARKET OPPORTUNITIES Increasing demand for early diagnosis, Expanding insurance coverage for testing, Technological advancements in testing methods, Rising maternal age and pregnancy risks, Growing awareness of genetic disorders
    KEY MARKET DYNAMICS rising maternal age, increased genetic awareness, favorable reimbursement policies, technological advancements, regulatory approvals
    COUNTRIES COVERED US

    Market Highlights

    Author
    Garvit Vyas
    Analyst

    Explore the profile of Garvit Vyas, one of our esteemed authors at Market Research Future, and access their expert research contributions in the field of market research and industry analysis

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    FAQs

    What is the expected market size of the US Non-Invasive Prenatal Testing Market in 2024?

    The US Non-Invasive Prenatal Testing Market is expected to be valued at 539.0 million USD in 2024.

    What is the projected market size for the US Non-Invasive Prenatal Testing Market by 2035?

    By 2035, the US Non-Invasive Prenatal Testing Market is projected to reach 1326.0 million USD.

    What is the expected CAGR for the US Non-Invasive Prenatal Testing Market from 2025 to 2035?

    The expected compound annual growth rate (CAGR) for the market is 8.528% from 2025 to 2035.

    Which type of non-invasive prenatal test is expected to have the largest market share in 2024?

    Cell-Free DNA Testing is expected to dominate the market with a valuation of 250.0 million USD in 2024.

    What is the market size for Biochemical Testing in the US Non-Invasive Prenatal Testing Market for 2024?

    The market for Biochemical Testing is valued at 150.0 million USD in 2024.

    Who are the key players in the US Non-Invasive Prenatal Testing Market?

    Major players include Illumina, LabCorp, Fulgent Genetics, Sequenom, and Myriad Genetics among others.

    What market size is anticipated for Combined Screening in the US Non-Invasive Prenatal Testing Market in 2024?

    Combined Screening is expected to be valued at 139.0 million USD in 2024.

    What are the growth opportunities in the US Non-Invasive Prenatal Testing Market?

    The market presents growth opportunities in advanced testing methods and increasing demand for accurate prenatal assessments.

    What challenges does the US Non-Invasive Prenatal Testing Market currently face?

    Challenges include regulatory hurdles and the need for continuous technological advancements.

    How does the market size for Cell-Free DNA Testing change by 2035?

    The market for Cell-Free DNA Testing is projected to grow significantly to 650.0 million USD by 2035.

    1. EXECUTIVE SUMMARY
    2. Market Overview
    3. Key Findings
    4. Market Segmentation
    5. Competitive Landscape
    6. Challenges and Opportunities
    7. Future Outlook
    8. MARKET INTRODUCTION
    9. Definition
    10. Scope of the study
    11. Research Objective
    12. Assumption
    13. Limitations
    14. RESEARCH METHODOLOGY
    15. Overview
    16. Data Mining
    17. Secondary Research
    18. Primary Research
    19. Primary Interviews and Information Gathering Process
    20. Breakdown of Primary Respondents
    21. Forecasting Model
    22. Market Size Estimation
    23. Bottom-Up Approach
    24. Top-Down Approach
    25. Data Triangulation
    26. Validation
    27. MARKET DYNAMICS
    28. Overview
    29. Drivers
    30. Restraints
    31. Opportunities
    32. MARKET FACTOR ANALYSIS
    33. Value chain Analysis
    34. Porter's Five Forces Analysis
    35. Bargaining Power of Suppliers
    36. Bargaining Power of Buyers
    37. Threat of New Entrants
    38. Threat of Substitutes
    39. Intensity of Rivalry
    40. COVID-19 Impact Analysis
    41. Market Impact Analysis
    42. Regional Impact
    43. Opportunity and Threat Analysis
    44. US Non-Invasive Prenatal Testing Market, BY Test Type (USD Million)
    45. Cell-Free DNA Testing
    46. Biochemical Testing
    47. Combined Screening
    48. US Non-Invasive Prenatal Testing Market, BY Application (USD Million)
    49. Fetal Gender Determination
    50. Chromosomal Abnormalities Screening
    51. Rhesus Disease Screening
    52. US Non-Invasive Prenatal Testing Market, BY Technology (USD Million)
    53. Next Generation Sequencing
    54. Microarray Analysis
    55. Polymerase Chain Reaction
    56. US Non-Invasive Prenatal Testing Market, BY End User (USD Million)
    57. Hospitals
    58. Diagnostic Laboratories
    59. Direct-to-Consumer Companies
    60. Competitive Landscape
    61. Overview
    62. Competitive Analysis
    63. Market share Analysis
    64. Major Growth Strategy in the Non-Invasive Prenatal Testing Market
    65. Competitive Benchmarking
    66. Leading Players in Terms of Number of Developments in the Non-Invasive Prenatal Testing Market
    67. Key developments and growth strategies
    68. New Product Launch/Service Deployment
    69. Merger & Acquisitions
    70. Joint Ventures
    71. Major Players Financial Matrix
    72. Sales and Operating Income
    73. Major Players R&D Expenditure. 2023
    74. Company Profiles
    75. Illumina
    76. Financial Overview
    77. Products Offered
    78. Key Developments
    79. SWOT Analysis
    80. Key Strategies
    81. LabCorp
    82. Financial Overview
    83. Products Offered
    84. Key Developments
    85. SWOT Analysis
    86. Key Strategies
    87. Fulgent Genetics
    88. Financial Overview
    89. Products Offered
    90. Key Developments
    91. SWOT Analysis
    92. Key Strategies
    93. Sequenom
    94. Financial Overview
    95. Products Offered
    96. Key Developments
    97. SWOT Analysis
    98. Key Strategies
    99. Myriad Genetics
    100. Financial Overview
    101. Products Offered
    102. Key Developments
    103. SWOT Analysis
    104. Key Strategies
    105. Bionano Genomics
    106. Financial Overview
    107. Products Offered
    108. Key Developments
    109. SWOT Analysis
    110. Key Strategies
    111. Genetic Technologies
    112. Financial Overview
    113. Products Offered
    114. Key Developments
    115. SWOT Analysis
    116. Key Strategies
    117. PerkinElmer
    118. Financial Overview
    119. Products Offered
    120. Key Developments
    121. SWOT Analysis
    122. Key Strategies
    123. Sema4
    124. Financial Overview
    125. Products Offered
    126. Key Developments
    127. SWOT Analysis
    128. Key Strategies
    129. Horizon Genomics
    130. Financial Overview
    131. Products Offered
    132. Key Developments
    133. SWOT Analysis
    134. Key Strategies
    135. Quest Diagnostics
    136. Financial Overview
    137. Products Offered
    138. Key Developments
    139. SWOT Analysis
    140. Key Strategies
    141. Roche
    142. Financial Overview
    143. Products Offered
    144. Key Developments
    145. SWOT Analysis
    146. Key Strategies
    147. Cleveland HeartLab
    148. Financial Overview
    149. Products Offered
    150. Key Developments
    151. SWOT Analysis
    152. Key Strategies
    153. Invitae
    154. Financial Overview
    155. Products Offered
    156. Key Developments
    157. SWOT Analysis
    158. Key Strategies
    159. Natera
    160. Financial Overview
    161. Products Offered
    162. Key Developments
    163. SWOT Analysis
    164. Key Strategies
    165. References
    166. Related Reports
    167. US Non-Invasive Prenatal Testing Market SIZE ESTIMATES & FORECAST, BY TEST TYPE, 2019-2035 (USD Billions)
    168. US Non-Invasive Prenatal Testing Market SIZE ESTIMATES & FORECAST, BY APPLICATION, 2019-2035 (USD Billions)
    169. US Non-Invasive Prenatal Testing Market SIZE ESTIMATES & FORECAST, BY TECHNOLOGY, 2019-2035 (USD Billions)
    170. US Non-Invasive Prenatal Testing Market SIZE ESTIMATES & FORECAST, BY END USER, 2019-2035 (USD Billions)
    171. PRODUCT LAUNCH/PRODUCT DEVELOPMENT/APPROVAL
    172. ACQUISITION/PARTNERSHIP
    173. MARKET SYNOPSIS
    174. US NON-INVASIVE PRENATAL TESTING MARKET ANALYSIS BY TEST TYPE
    175. US NON-INVASIVE PRENATAL TESTING MARKET ANALYSIS BY APPLICATION
    176. US NON-INVASIVE PRENATAL TESTING MARKET ANALYSIS BY TECHNOLOGY
    177. US NON-INVASIVE PRENATAL TESTING MARKET ANALYSIS BY END USER
    178. KEY BUYING CRITERIA OF NON-INVASIVE PRENATAL TESTING MARKET
    179. RESEARCH PROCESS OF MRFR
    180. DRO ANALYSIS OF NON-INVASIVE PRENATAL TESTING MARKET
    181. DRIVERS IMPACT ANALYSIS: NON-INVASIVE PRENATAL TESTING MARKET
    182. RESTRAINTS IMPACT ANALYSIS: NON-INVASIVE PRENATAL TESTING MARKET
    183. SUPPLY / VALUE CHAIN: NON-INVASIVE PRENATAL TESTING MARKET
    184. NON-INVASIVE PRENATAL TESTING MARKET, BY TEST TYPE, 2025 (% SHARE)
    185. NON-INVASIVE PRENATAL TESTING MARKET, BY TEST TYPE, 2019 TO 2035 (USD Billions)
    186. NON-INVASIVE PRENATAL TESTING MARKET, BY APPLICATION, 2025 (% SHARE)
    187. NON-INVASIVE PRENATAL TESTING MARKET, BY APPLICATION, 2019 TO 2035 (USD Billions)
    188. NON-INVASIVE PRENATAL TESTING MARKET, BY TECHNOLOGY, 2025 (% SHARE)
    189. NON-INVASIVE PRENATAL TESTING MARKET, BY TECHNOLOGY, 2019 TO 2035 (USD Billions)
    190. NON-INVASIVE PRENATAL TESTING MARKET, BY END USER, 2025 (% SHARE)
    191. NON-INVASIVE PRENATAL TESTING MARKET, BY END USER, 2019 TO 2035 (USD Billions)
    192. BENCHMARKING OF MAJOR COMPETITORS

    US Non-Invasive Prenatal Testing Market Segmentation

    • Non-Invasive Prenatal Testing Market By Test Type (USD Million, 2019-2035)

      • Cell-Free DNA Testing
      • Biochemical Testing
      • Combined Screening

     

    • Non-Invasive Prenatal Testing Market By Application (USD Million, 2019-2035)

      • Fetal Gender Determination
      • Chromosomal Abnormalities Screening
      • Rhesus Disease Screening

     

    • Non-Invasive Prenatal Testing Market By Technology (USD Million, 2019-2035)

      • Next Generation Sequencing
      • Microarray Analysis
      • Polymerase Chain Reaction

     

    • Non-Invasive Prenatal Testing Market By End User (USD Million, 2019-2035)

      • Hospitals
      • Diagnostic Laboratories
      • Direct-to-Consumer Companies

     

     

     

     

     

     

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