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    US Metagenomic Sequencing Market

    ID: MRFR/LS/18432-HCR
    100 Pages
    Garvit Vyas
    October 2025

    US Metagenomic Sequencing Market Research Report By Product & Service (Reagents and Consumables, Instruments, Services) and By Technology (Shotgun Metagenomic Sequencing, 16s rRNA Sequencing, Whole Genome Sequencing and De Novo Assembly, Metatranscriptomic) - Forecast to 2035

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    US Metagenomic Sequencing Market Infographic
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    US Metagenomic Sequencing Market Summary

    As per MRFR analysis, the US metagenomic sequencing market size was estimated at 163.2 USD Million in 2024.. The US metagenomic sequencing market is projected to grow from 187.66 USD Million in 2025 to 758.53 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 14.99% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The US metagenomic sequencing market is poised for substantial growth driven by technological advancements and increasing research funding.

    • Technological advancements are enhancing the capabilities of metagenomic sequencing, leading to more accurate and efficient analyses.
    • The largest segment in the US market is driven by applications in infectious disease research, reflecting a growing focus on public health.
    • The fastest-growing segment is likely to be personalized medicine, as demand for tailored healthcare solutions continues to rise.
    • Rising demand for personalized medicine and advancements in bioinformatics tools are key drivers propelling market expansion.

    Market Size & Forecast

    2024 Market Size 163.2 (USD Million)
    2035 Market Size 758.53 (USD Million)

    Major Players

    Illumina (US), Thermo Fisher Scientific (US), BGI Genomics (CN), Qiagen (DE), Roche (CH), PerkinElmer (US), Agilent Technologies (US), Oxford Nanopore Technologies (GB)

    US Metagenomic Sequencing Market Trends

    The metagenomic sequencing market is currently experiencing a notable evolution, driven by advancements in technology and increasing applications across various sectors. The integration of high-throughput sequencing methods has enabled researchers to analyze complex microbial communities with unprecedented accuracy. This capability is particularly valuable in fields such as environmental monitoring, agriculture, and healthcare, where understanding microbial diversity can lead to significant insights. Furthermore, the growing emphasis on personalized medicine and the need for rapid diagnostics are propelling the demand for metagenomic sequencing solutions. As a result, stakeholders are increasingly investing in research and development to enhance sequencing technologies and expand their applications. In addition, regulatory frameworks and funding initiatives from government bodies are fostering innovation within the metagenomic sequencing market. These efforts aim to streamline the approval processes for new technologies and promote collaboration among academic institutions, industry players, and healthcare providers. The focus on sustainable practices and the need for effective disease management strategies are likely to further stimulate growth in this sector. Overall, the metagenomic sequencing market appears poised for continued expansion, with a diverse range of applications and a strong push towards technological advancements.

    Technological Advancements

    Recent innovations in sequencing technologies are transforming the metagenomic sequencing market. The development of more efficient and cost-effective sequencing platforms is enabling researchers to conduct large-scale studies with greater ease. These advancements are likely to enhance the accuracy and speed of microbial analysis, making it more accessible to various industries.

    Increased Research Funding

    There is a noticeable rise in funding for metagenomic research from government agencies and private organizations. This financial support is aimed at exploring the potential applications of metagenomic sequencing in areas such as public health, agriculture, and environmental science. Such investments are expected to drive innovation and expand the market.

    Regulatory Support

    Regulatory bodies are increasingly recognizing the importance of metagenomic sequencing in addressing public health challenges. Initiatives to establish clear guidelines and standards for the use of sequencing technologies are emerging. This regulatory support may facilitate the adoption of metagenomic sequencing in clinical settings, thereby broadening its impact.

    US Metagenomic Sequencing Market Drivers

    Advancements in Bioinformatics Tools

    The metagenomic sequencing market is significantly impacted by advancements in bioinformatics tools that facilitate data analysis and interpretation. As sequencing technologies generate vast amounts of data, the need for sophisticated analytical tools becomes paramount. Enhanced bioinformatics capabilities enable researchers to process and analyze complex metagenomic datasets more efficiently, leading to more accurate insights into microbial communities. In the US, the bioinformatics market is expected to grow to approximately $10 billion by 2025, driven by the increasing demand for data-driven decision-making in various sectors, including healthcare and environmental science. This driver underscores the importance of integrating advanced bioinformatics solutions into the metagenomic sequencing market, as they enhance the overall utility and applicability of sequencing data.

    Rising Demand for Personalized Medicine

    The metagenomic sequencing market is experiencing a notable surge in demand for personalized medicine. As healthcare shifts towards tailored treatments, the ability to analyze individual microbiomes becomes crucial. This trend is driven by advancements in sequencing technologies that allow for more precise and comprehensive analysis of microbial communities. In the US, the market for personalized medicine is projected to reach approximately $350 billion by 2025, indicating a robust growth trajectory. The integration of metagenomic sequencing into clinical practices enhances the understanding of patient-specific responses to therapies, thereby improving treatment outcomes. Consequently, this driver is pivotal in shaping the metagenomic sequencing market, as healthcare providers increasingly rely on detailed microbial insights to inform their clinical decisions.

    Growing Interest in Environmental Monitoring

    The metagenomic sequencing market is witnessing a growing interest in environmental monitoring, particularly in assessing microbial diversity and ecosystem health. As environmental concerns escalate, there is an increasing emphasis on understanding the role of microorganisms in various ecosystems. Metagenomic sequencing provides a powerful tool for monitoring microbial communities in soil, water, and air, enabling researchers to track changes in biodiversity and detect pollutants. In the US, the environmental monitoring market is projected to reach $20 billion by 2026, with a significant portion attributed to microbial analysis. This driver highlights the potential of metagenomic sequencing to contribute to environmental sustainability efforts, as stakeholders seek to leverage microbial insights for better management of natural resources.

    Increased Collaboration Between Academia and Industry

    The metagenomic sequencing market is benefiting from increased collaboration between academia and industry, fostering innovation and accelerating research. Partnerships between academic institutions and biotechnology companies are becoming more common, as they seek to leverage each other's strengths in research and development. This collaboration is particularly evident in the development of novel sequencing technologies and applications. In the US, funding for academic-industry partnerships has seen a rise, with federal grants supporting collaborative projects aimed at advancing metagenomic research. This driver is likely to enhance the metagenomic sequencing market by facilitating the translation of research findings into practical applications, ultimately leading to improved products and services in the field.

    Expansion of Applications in Infectious Disease Research

    The metagenomic sequencing market is significantly influenced by the expansion of applications in infectious disease research. With the increasing prevalence of antibiotic-resistant pathogens, there is a pressing need for innovative diagnostic tools. Metagenomic sequencing offers a comprehensive approach to identify and characterize pathogens directly from clinical samples, facilitating timely and accurate diagnoses. In the US, the market for infectious disease diagnostics is expected to grow at a CAGR of around 8% through 2025. This growth is likely to be fueled by the rising incidence of infectious diseases and the need for rapid identification methods. As researchers and clinicians adopt metagenomic sequencing for its ability to provide insights into complex microbial communities, this driver is expected to play a crucial role in the market's evolution.

    Market Segment Insights

    Metagenomic Sequencing Market Product & Service Insights

    The US Metagenomic Sequencing Market is witnessing significant evolution within its Product and Service segment, which encompasses essential components such as Reagents and Consumables, Instruments, and Services. Reagents and Consumables remain critical to the market, as they provide the necessary materials for sample processing and analysis.

    The importance of high-quality reagents is underscored by their direct impact on the accuracy and reliability of sequencing results, making them a crucial aspect of successful metagenomic studies. Instruments play a pivotal role in advancing the capabilities of metagenomic sequencing, as innovative technologies facilitate higher throughput and improved data generation efficiency.

    As the need for comprehensive genomic data continues to rise in research and clinical applications, cutting-edge instrumentation is poised to dominate the market landscape, driving further advancements in metagenomics. Services within this segment are also gaining traction, providing essential support such as data analysis, bioinformatics, and project consultation, which assist researchers and institutions in navigating the complexities of metagenomic data interpretation.

    The demand for specialized services highlights the growing reliance on expert knowledge in the field, as well as the increasing importance of collaboration between service providers and researchers. Collectively, these components of the Product and Service segment not only address current market needs but also contribute to the ongoing expansion and growth within the US Metagenomic Sequencing Market, reinforcing the sector’s potential in diverse applications ranging from environmental studies to human health investigations.

    As the landscape changes, the continuous improvement in technologies and offerings will pave the way for enhanced research capabilities and new opportunities, further solidifying the significance of these elements in the overall market dynamics. Through such advancements, this segment plays an integral role in shaping the future of genomic research and personalized medicine in the United States.

    Metagenomic Sequencing Market Technology Insights

    The US Metagenomic Sequencing Market, particularly in the Technology segment, plays a crucial role in advancing our understanding of microbial diversity and functionality. Techniques such as Shotgun Metagenomic Sequencing allow for comprehensive analyses of complex microbial communities, making it essential for environmental monitoring and clinical diagnostics.

    Meanwhile, 16s rRNA Sequencing stands out for its precision in identifying and classifying bacteria, serving as a foundational method in both research and clinical settings. Moreover, Whole Genome Sequencing and De Novo Assembly are pivotal in unraveling the genomes of various organisms, leading to significant discoveries in genomics and microbiomics.

    The Metatranscriptomic approach further enhances this by providing insights into gene expression within microbial communities, which has implications for health and disease management. With these technologies, the US Metagenomic Sequencing Market is positioned to enrich our understanding of microbial ecosystems, contributing significantly to fields such as healthcare, agriculture, and environmental science.

    Overall, these techniques drive innovation while offering vast opportunities for research, product development, and applications across numerous industries.

    Get more detailed insights about US Metagenomic Sequencing Market

    Key Players and Competitive Insights

    The metagenomic sequencing market is characterized by a dynamic competitive landscape, driven by advancements in technology and increasing demand for genomic data across various sectors, including healthcare, environmental monitoring, and agriculture. Key players such as Illumina (US), Thermo Fisher Scientific (US), and BGI Genomics (CN) are at the forefront, each adopting distinct strategies to enhance their market presence. Illumina (US) focuses on innovation through continuous development of next-generation sequencing technologies, while Thermo Fisher Scientific (US) emphasizes strategic partnerships to expand its product offerings and market reach. BGI Genomics (CN) leverages its cost-effective solutions to penetrate diverse markets, thereby intensifying competition among these major players.

    The business tactics employed by these companies include localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure appears moderately fragmented, with a mix of established players and emerging companies vying for market share. The collective influence of these key players shapes the competitive dynamics, as they continuously adapt to evolving customer needs and technological advancements.

    In October 2025, Illumina (US) announced a collaboration with a leading healthcare provider to integrate its sequencing technology into routine clinical diagnostics. This strategic move is likely to enhance patient outcomes by enabling more personalized treatment plans, thereby solidifying Illumina's position as a leader in the clinical genomics space. The partnership underscores the growing trend of integrating genomic data into healthcare, which may reshape treatment paradigms.

    In September 2025, Thermo Fisher Scientific (US) launched a new metagenomic sequencing platform designed to streamline workflows and reduce turnaround times for researchers. This innovation is expected to attract a broader customer base, particularly in academic and research institutions, as it addresses the increasing demand for rapid and reliable sequencing solutions. The launch reflects Thermo Fisher's commitment to maintaining its competitive edge through technological advancements.

    In August 2025, BGI Genomics (CN) expanded its operations in the US by establishing a new research facility focused on environmental metagenomics. This strategic expansion is indicative of BGI's intent to capitalize on the growing interest in environmental applications of metagenomics, potentially positioning the company as a key player in this niche market. The move may also enhance collaboration with local research institutions, fostering innovation in environmental monitoring.

    As of November 2025, current competitive trends in the metagenomic sequencing market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence (AI) into sequencing processes. Strategic alliances among key players are increasingly shaping the landscape, facilitating knowledge sharing and resource optimization. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability, as companies strive to meet the growing demands of diverse sectors.

    Key Companies in the US Metagenomic Sequencing Market market include

    Industry Developments

    The US Metagenomic Sequencing Market has recently seen significant developments with companies like Illumina and Thermo Fisher Scientific advancing their product offerings aimed at enhancing genomic research, particularly in areas like environmental and clinical microbiology. In September 2023, Illumina announced the launch of its latest sequencing platform designed to streamline workflows, which has garnered attention in the research community.

    Growth in market valuation for companies involved in metagenomic sequencing, including BioRad Laboratories and Agilent Technologies, reflects a rising demand for innovative diagnostic tools amid increasing emphasis on personalized medicine. Additionally, in August 2023, F. Hoffmann-La Roche expanded its genomic capabilities through the acquisition of a key technology firm, further consolidating its position in the market.

    Current affairs also highlight collaborations among companies such as Oxford Nanopore Technologies and Genomatix to enhance data analysis techniques in metagenomic studies. Over the past few years, investments in research by Merck KGaA and Qiagen have driven advancements in metagenomic technologies, with the US government advocating for increased funding for genomic research initiatives.

    This momentum indicates a future ripe with potential for advancements in metagenomic sequencing in the US market.

    Future Outlook

    US Metagenomic Sequencing Market Future Outlook

    The metagenomic sequencing market is projected to grow at a 14.99% CAGR from 2024 to 2035, driven by advancements in technology, increasing demand for personalized medicine, and rising applications in environmental monitoring.

    New opportunities lie in:

    • Development of portable metagenomic sequencing devices for field research.
    • Partnerships with pharmaceutical companies for drug discovery applications.
    • Expansion of bioinformatics services to enhance data analysis capabilities.

    By 2035, the metagenomic sequencing market is expected to achieve substantial growth and innovation.

    Market Segmentation

    US Metagenomic Sequencing Market Technology Outlook

    • Shotgun Metagenomic Sequencing
    • 16s rRNA Sequencing
    • Whole Genome Sequencing and De Novo Assembly
    • Metatranscriptomic

    US Metagenomic Sequencing Market Product & Service Outlook

    • Reagents and Consumables
    • Instruments
    • Services

    Report Scope

    MARKET SIZE 2024 163.2(USD Million)
    MARKET SIZE 2025 187.66(USD Million)
    MARKET SIZE 2035 758.53(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 14.99% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Illumina (US), Thermo Fisher Scientific (US), BGI Genomics (CN), Qiagen (DE), Roche (CH), PerkinElmer (US), Agilent Technologies (US), Oxford Nanopore Technologies (GB)
    Segments Covered Product & Service, Technology
    Key Market Opportunities Advancements in bioinformatics tools enhance data analysis capabilities in the metagenomic sequencing market.
    Key Market Dynamics Technological advancements drive innovation and competition in the metagenomic sequencing market, enhancing research capabilities and applications.
    Countries Covered US

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    FAQs

    What is the expected market size of the US Metagenomic Sequencing Market in 2024?

    The US Metagenomic Sequencing Market is expected to be valued at 163.2 million USD in 2024.

    What is the projected market size of the US Metagenomic Sequencing Market by 2035?

    By 2035, the market is anticipated to reach a value of 905.0 million USD.

    What is the expected compound annual growth rate (CAGR) for the US Metagenomic Sequencing Market from 2025 to 2035?

    The market is projected to grow at a CAGR of 16.85% from 2025 to 2035.

    Which product segment is expected to dominate the US Metagenomic Sequencing Market in 2035?

    By 2035, the 'Reagents and Consumables' segment is expected to dominate, reaching 350.0 million USD.

    What challenges and opportunities are present in the US Metagenomic Sequencing Market?

    Ongoing technological advancements and increasing applications in personalized medicine present significant opportunities, while regulatory hurdles may pose challenges.

    How is the competitive landscape of the US Metagenomic Sequencing Market characterized?

    Key players in the market include Illumina, BioRad Laboratories, and Thermo Fisher Scientific, among others, contributing to a competitive landscape.

    How has the market for instruments evolved by 2035 in the US Metagenomic Sequencing Market?

    The instruments segment is expected to grow to 250.0 million USD by 2035, indicating substantial growth in demand.

    What is the expected market value for services in the US Metagenomic Sequencing Market in 2035?

    By 2035, the services segment is expected to reach a market value of 305.0 million USD.

    What key applications drive the growth of the US Metagenomic Sequencing Market?

    Growth is driven by applications in environmental monitoring, clinical diagnostics, and microbiome analysis.

    What regional trends can be observed in the US Metagenomic Sequencing Market?

    There is a noticeable increase in investment and research initiatives in the US, positioning it as a leading region in this market.

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