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Surgical Sealants and Adhesives Market Size

ID: MRFR//5540-HCR | 100 Pages | Author: Rahul Gotadki| November 2024

Myriad factors determine the nature of the market for surgical sealants and adhesives. One of these is the increasing number of surgical procedures globally. The impact of technology on the market is also very significant. This has led to the development of medical adhesives and sealants with better properties, such as faster curing, better biocompatibility, and higher strength through continuous innovation in this field. For instance, regulatory frameworks and approvals have been pivotal in shaping the market for surgical sealants and adhesives since most medical products are sensitive. Market players, therefore, appreciate compliance with regulatory provisions to ensure their products meet safety requirements as stipulated by such guidelines. Complying with regulations ensures that healthcare professionals trust them while at the same time enabling them to access new markets.
Additionally, the macroeconomic environment and patterns of health expenditure have large impacts on the dynamics of shellacs used in surgery. Because they want to make it excellent, nations increase their financing on the health sector, which leads to increased costs incurred therein, fundamentally resulting in escalated levels of spending. Financial capacity determines the extent of using modern medical technologies, including shellacs used in surgery, among other things like suturing needles. The competitive landscape is another factor that shapes this market significantly, as there are many players from various niches, starting from pharmaceutical majors up to small manufacturers who create the conditions for innovations and the product development process itself. Intense competition is prompted by companies that try differentiating their offers with unusual features, original prices, or peculiar positioning in the marketplace, which customers usually take into account when selecting a particular brand or type they need during operation performance.
Moreover, awareness within the healthcare profession community, besides patients, contributes significantly towards shaping dynamics prevailing within the marketplace under consideration at present times today or even tomorrow. This means that if people become more aware of the advantages associated with use hereof rather than traditional ways like stapling threads, then the number of users will definitely rise dramatically. Dissemination activities conducted by manufacturers themselves, as well as healthcare providers, help inform doctors and patients about opportunities, applications, or correct ways of application, respectively. The market for surgical sealants and adhesives can also be affected by global health issues like the COVID-19 pandemic. This has been illustrated through increased health supply chain robustness and preparedness, which have emphasized medical products and equipment recently. When a crisis strikes, the need for efficient solutions for closing wounds becomes more critical, hence the dynamics of the market during such periods.

Covered Aspects:

Report Attribute/Metric Details
Growth Rate   10.4% : 2023-2032  Base Year  2021  Forecast Period  2023-2032  Historical Data  2020  Forecast Units  Value (USD Billion  Report Coverage  Revenue Forecast, Competitive Landscape, Growth Factors, and Trends  Segments Covered  By Product, Indication, Application  Geographies Covered  North America, Europe, Asia-Pacific, and Rest of the World (RoW)  Key Vendors  R. Bard, Inc. (US), Johnson & Johnson (UK), Baxter International, Inc. (US), Medtronic plc (US), B. Braun Melsungen AG (Germany), Cohera Medical, Inc. (US), Sanofi Group (France), Sealantis, Ltd (Israel), Vivostat A/S (Denmark), and Ocular Therapuetix, Inc. (US)  Key Market Opportunities  Increasing surgical procedures, development of healthcare infrastructure and investments by industry players  Key Market Drivers·  Growing prevalence and incidence of various disorders·  Growth in the number of accidents·  Growth in the number of surgeries 

Global Surgical Sealants and Adhesives Market Overview 


According to the research reports by MRFR, the global market for surgical sealants and adhesives is estimated to flourish at a healthy CAGR of over 10.4% to reach USD 6.51 billion over the assessment era 2023-2032. 


Surgical sealants and adhesives are added to stitches to help prevent liquid and air leaks. They may also be used to replace staples and sutures for better closure, quicker implementation, a simpler and less painful procedure, and less blood loss without the need for removal. 


Surgical Sealants and Adhesives Market


In December 2023, RevBio, a US-based firm, obtained permission from the Food and Drug Administration (FDA) to start a first-in-human (FIH) clinical trial of its bone glue called Tetranite indicated cranial flap fixing, a synthetic substitute material for bonding human skull. The regulatory support and advances in materials are expected to drive innovation in the industry. 


In June 2023, the U.S. Food and Drug Administration (FDA) authorized LiquiBandFix8 for Pre-Market Approval (PMA), a device that contains cyanoacrylate adhesive used during hernia surgery operations.


In May 2023, POWERSEALTM Sealer/Divider was launched by Olympus in many parts, including Europe.


In March 2023, Animus Surgical showed off a new transparent, biodegradable, non-toxic hydrogel wound sealant.


In January 2023, Grifols, one of the major players in plasma medicine, disclosed positive top-line results from its phase 3b study involving fibrin sealant (FS), which was aimed at treating bleeding that arose out of surgeries for pediatric patients. These positive results emanating from various studies and investigations conducted by key manufacturers will be essential for the introduction of novel products into the market.


In May 2022, Ethicon –a big player in this industry, acquired GATT Technologies based out of the Netherlands. This acquisition employs different synthetic polymers to design hemostatic and sealant products.


Ethicon is one of the leading surgical solutions providers that launched ENSEAL X1 Straight Jaw Tissue Sealer specifically in April 2022, targeting tissue sealing. Such product launches for tissue sealing would propel segment growth over the coming years.


In 2021, Ethicon purchased Tissuemed—a supplier of surgical sealant solutions—so as to expand its offering to surgeons outside the USA.



In recent years, the global market for surgical sealants and adhesives has grown dramatically. The increased frequency and incidence of numerous ailments around the world are largely responsible for the market's rise. Furthermore, one of the key factors driving the Surgical Sealants and Adhesives Market's expansion is the number of incidents. The escalating reported prevalence rates of numerous disorders such as obesity and cardiovascular disease (CVD), as well as the rising incidence of trauma and the number of accidents and sports-related injuries, have all contributed to an increase in surgical procedures performed worldwide. The necessity to manage blood loss in patients, as well as ongoing R&D to bring innovative products to market, are all contributing to Surgical Sealants and Adhesives Market growth. Surgical sealants and adhesives are becoming more widely used in aesthetic treatments due to improved cosmetic outcomes.


Surgical Sealants and Adhesives Market Segment Insights


The global surgical sealants and adhesives market has been segmented into product, indication, application, and end user.


Surgical Sealants and Adhesives Product Insights


Based on product, has been segmented into natural/biological sealants and adhesives and synthetic and semisynthetic sealants and adhesives. The natural/biological sealants and adhesives and synthetic segment is accounted for the largest share segment of the market.


Surgical Sealants and Adhesives Indication Insights


The market, by indication, has been segmented into surgical hemostasis, tissue sealing, and tissue engineering.


Surgical Sealants and Adhesives Application Insights


The market, by application, has been segmented into general surgeries, cardiovascular surgeries, central nervous system surgeries, orthopedic surgeries, urological surgeries, and others.


Surgical Sealants and Adhesives Regional Insights


The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The surgical sealants and adhesives market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.


The European surgical sealants and adhesives market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.


The surgical sealants and adhesives market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The market in the Middle East & Africa has been segmented into the Middle East and Africa.


Surgical Sealants and Adhesives Market Top Key Players


Some of the key players in the global surgical sealants and adhesives market are:



  • R. Bard, Inc. (US)

  • Johnson & Johnson (UK)

  • Baxter International, Inc. (US)

  • Medtronic plc (US)

  • B. Braun Melsungen AG (Germany)

  • Cohera Medical, Inc. (US)

  • Sanofi Group (France)

  • Sealantis, Ltd (Israel)

  • Vivostat A/S (Denmark)

  • Ocular Therapeutix, Inc. (US)


Regional Market Summary


Geographically, the Americas is anticipated to dominate the global surgical sealants and adhesives market owing to a well-developed healthcare sector, increasing surgeries, technological advancement, and rising geriatric population.


Europe is expected to hold the second largest position in the global surgical sealants and adhesives market. The market growth in this region is attributed to the increasing surgical procedures and developed healthcare infrastructure.


The surgical sealants and adhesives market in Asia-Pacific region consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia-Pacific. The Asia-Pacific region is expected to be fastest growing region owing to the huge patient population of chronic diseases in the countries such as India and China.


The Middle East & Africa has the least share of the market. Majority of the market of this region is expected to be held by the Middle East region due to a well-developed healthcare sector and growing government initiatives for the healthcare sector.Recent Development



  • December 2021- Becton, Dickinson, and Company (BD), a leading global medical technology company, has announced the acquisition of Tissuemed, a self-adhesive surgical sealant films developer, for an unrevealed amount. Tissuepatch, Tissuemed's sealant technology, holds to tissues to offer prevention from leaks during surgical incisions and can be used to control internal bleeding. With a transparent, flexible, and thin composition, the technology assists clinicians in sealing stapled or sutured tissues against leakage of blood, air, and other fluids, including cerebrospinal fluid (CSF), after surgical procedures.

  • October 2021- An international research team led by McGill University has successfully revealed the cellular mechanism responsible causing the underwater adhesive fabricated by the mussels.


Surgical Sealants and Adhesives Market Segmentation


Surgical Sealants and Adhesives Product Outlook



  • Natural/Biological Sealants and Adhesives


    • Natural/Biological Sealants and Adhesives, By Type


      • Polypeptide/Protein-based Sealants and Adhesives


        • Fibrin Based

        • Gelatin Based

        • Collagen Based

        • Albumin Based


      • Polysaccharide-based Sealants and Adhesives


        • Chitosan Based

        • Others


      • Natural/Biological Sealants and Adhesives, by Origin


        • Human Blood Based

        • Animal Based




  • Synthetic and Semi-synthetic Sealants and Adhesives


    • Cyanoacrylates

    • Polyethylene glycol Based Hydrogels

    • Urethane Based

    • Others



Surgical Sealants and Adhesives Indication Outlook



Surgical Sealants and Adhesives Application Outlook



  • General Surgeries

  • Cardiovascular Surgeries

  • Central Nervous System Surgeries

  • Orthopedic Surgeries

  • Urological Surgeries

  • Others


Surgical Sealants and Adhesives Regional Outlook



  • Americas


    • North America


      • US

      • Canada


    • South America


  • Europe


    • Western Europe


      • Germany

      • France

      • Italy

      • Spain

      • UK

      • Rest of Western Europe


    • Eastern Europe


  • Asia-Pacific


    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Rest of Asia-Pacific


  • The Middle East & Africa


    • Middle East

    • Africa



Recent Development


Mallinckrodt sold two hemostat and sealant products to Baxter in 2018. PREVELEAK surgical sealant is used in vascular reconstruction, and RECOTHROM Thrombin topical hemostat is the first and only stand-alone recombinant thrombin. Baxter was able to increase its product options and gain a larger part of the global surgical sealants and adhesives market as a result of this acquisition. Sealantis, an Israeli medical device firm with a patent-protected alga-mimetic sealant technology platform in development for a wide range of surgical indications, was acquired by AMS in 2019. This helped AMS strengthen its position in the high-margin internal surgery sector by providing a technological platform and delivery methods with substantial potential across a variety of applications.

Intended Audience:



  • Surgical Sealants and Adhesives Manufacturers and vendors

  • Various research and consulting firms

  • Surgical Sealants and Adhesives Distributors

  • Hospitals


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