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Pemphigus Vulgaris drugs market is a distinct sector that focuses on the special challenges of Pemphigus Vulgaris, which is an uncommon and life-threatening blistering autoimmune disease involving the skin and mucous membranes. The market is important in providing pharmaceutical products for managing Pemphigus vulgaris, which consequently leads to very painful filled blisters causing very severe wound damage on the skin or mucous membrane. These diseases need specific medicines blocking immunity against vesicle formation.
In Pharmaceutical Pemphigus Vulgaris Market, immunosuppressants are one of the broad categories. For instance, among corticosteroids prednisone as first-line therapy controls inflammation and overactive immune system responses that are excessive. Nonetheless, prolonged use of corticosteroids can result into serious side effects thus other immunosuppressive agents should exist. Thus, this market provides second line therapies including azathioprine, mycophenolate mofetil and rituximab among others not based on the premise of corticosteroids with an objective of disease control.
Biological treatments such as riutixumab-a monoclonal antibody anti-Cd20 are also important in Pharmaceutical Pemphigus Vulgaris Market in targeting specific parts of human’s immune response system that have proved effective in terms of pemphigus vulgaris. Biologics offer patients who might not respond well to normal options for immunosuppressant therapy or experience extreme effects from corticosteroid usage alternative ways to manage their conditions.
One major hurdle encountered within the Pharmaceutical Pemphigus Vulgaris Market is personalization of treatment plans due to differences in individual reaction as well as severity of illness. In order to ensure maximum benefits with minimum possible adverse impacts as a result intervention plans should be tailored individually for each patient’s treatment. That’s why market is involved in ongoing research and clinical trials aimed at improving treatment protocols as well as exploring new therapeutic options for Pemphigus Vulgaris.
Additionally, Pharmaceutical Pemphigus Vulgaris Market highlights the importance of patient education and support in the management of this rare and complex disorder like pemphigus vulgaris. Health care professionals should be working with patients while managing a chronic autoimmune disease like this to ensure they adhere to their drugs prescribed, monitor side effects that may be potential and address psychosocial outcomes. Pharmaceutical companies usually sponsor patient advocacy programs which aim at informing those people affected by pemphigus vulgaris about it.
Development of the Pemphigus vulgaris market is focused towards targeted therapies and precision medicine approaches for pemphigus vulgaris. Understanding immunological basis of the disease has resulted into identification of newer molecules that can be pursued based on novel targets whose activity may be more specific than traditional agents. At the same time, within the Pharmaceutical Pemphigus Vulgaris Market, firms engage themselves in research collaborations together with partnerships to hasten the progress towards alternative therapies which might result into improvement among people living with this rather intricate autoimmune disorder.
Covered Aspects:
| Report Attribute/Metric | Details |
|---|---|
| Growth Rate | Â 9.10% |
Pemphigus Vulgaris Market Highlights:
Global Pemphigus Vulgaris Market Overview
Pemphigus Vulgaris Market Size was valued at USD 1.36 Billion in 2023. The Global Pemphigus Vulgaris industry is projected to grow from USD 1.52 Billion in 2024 to USD 4.83 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.36% during the forecast period (2024 - 2032).
Pemphigus Vulgaris is a type of autoimmune disease in which the antibodies produced against the bacteria attack the healthy cells and causes skin problems. Pemphigus Vulgaris affects both men and women, but middle- and old-aged people are more likely to develop this condition.
Pemphigus Vulgaris Market Trends
The key factors responsible for influencing the market growth are the increasing prevalence of pemphigus vulgaris, rising bacterial and viral infection, and the growing prevalence of cancer. The side effects associated with the medication and increase in geriatric population are also estimated to drive the market during the forecast period. However, factors such as high cost related to treatment, unfavorable reimbursement situation, and lack of awareness are expected to restrain the market growth
Pemphigus vulgaris is one of the most life-threatening autoimmune skin disorders that occurs due to various reasons such as bacterial infection, increasing pollution, and side effects of some medications. According to the National Organization for Rare Disorders (NORD), 2015, the prevalence of pemphigus was high within the US and Europe affecting approximately 0.7 to 5 people per 1,000,000 each year in the overall population. It was also mentioned that pemphigus foliaceus a form of pemphigus vulgaris has a high prevalence in Africa and some rural areas in the world.
According to the International Pemphigus & Pemphigoid Foundation, it was predicted that approximately 40,000 to 50,000 people across the world and 2,500 people in the US were diagnosed with pemphigus disorder in 2017. The increase in the prevalence of pemphigus vulgaris across the globe is expected to drive market growth during the forecast period from 2024 to 2032.
Pemphigus Vulgaris Market Segment Insights
Pemphigus Vulgaris Treatment Insights
The global pemphigus vulgaris market, by treatment, has been segmented into corticosteroids, immunosuppressants, biological therapies, and intravenous immunoglobulin (IVIG) therapy.
Pemphigus Vulgaris Route of Administration Insights
Based on the route of administration, the market has been classified as intravenous, subcutaneous, and oral.
Pemphigus Vulgaris End User Insights
By end user, the global pemphigus vulgaris market has been categorized as hospitals & clinics, specialty dermatology clinics, and research & academic laboratories.
Pemphigus Vulgaris Regional Insights
The global pemphigus vulgaris market, based on region, is divided into the Americas, Europe, Asia-Pacific, and the Middle East and Africa.
The Americas accounted for the largest market share in 2032 and is estimated to dominate the global pemphigus vulgaris market. The Americas accounts for the largest regional market owing to the increasing prevalence of pemphigus vulgaris, increasing geriatric population, and raising funding for the research & development of skin diseases. According to the National Center for Biotechnology Information 2014, it was predicted that the prevalence of pemphigus vulgaris in the US is in the range of 0.76 to 5 new cases per million every year. Also, according to the International Pemphigus & Pemphigoid Foundation, it was projected that approximately 2,500 people in the US suffered from pemphigus disorder in 2017.
Europe accounted for the second-largest market share in 2017 due to extensive R&D for pemphigus vulgaris, increasing funding, and growing adoption of the technology within the region. Asia-Pacific is expected to contribute to the market growth for pemphigus vulgaris during the forecast period owing to rising therapeutic demand for pemphigus vulgaris and rapidly evolving healthcare sector. On the other hand, the Middle East & Africa is expected to observe slow growth due to low per capita disposable incomes, lack of awareness, and less exposure to healthcare services in this region.
Pemphigus Vulgaris Market Top Key Players
The prominent players in the global pemphigus vulgaris market are
- Almirall, SA
- Argenx SE
- Biogen Inc.
- F. Hoffmann-La Roche
- Syntimmune
- Pfizer Inc.
- Novartis AG
- Sanofi
- Janssen Global Services, LLC
- Principia Biopharma
Some of the key strategies followed by players operating in the global pemphigus vulgaris market were innovation, product development, and acquisition & mergers.
- In December 2017, Almirall SA and Athenex entered into a strategic partnership to develop and commercialize KX2-391 in the US and Europe for the treatment of actinic keratosis.
- In January 2018, Pandion Therapeutics, a start-up led by former executives at Pfizer and Biogen, attracted USD 58 million in financing for the development of a new class of drugs that could tweak the immune system without triggering significant side effects.
- In February 2018, Roche announced that the US Food and Drug Administration (FDA) had accepted the company’s supplemental biologics license application (SBLA) and granted priority review for the use of MabThera/Rituxan (Rituximab) for the treatment of pemphigus vulgaris (PV), a rare, life-threatening condition characterized by progressive painful blistering of the skin and mucous membranes.
Pemphigus Vulgaris Market Segmentation
Pemphigus Vulgaris Treatment Outlook
- Corticosteroids
- Immunosuppressants
- Biological Therapies
- Intravenous Immunoglobulin (IVIG) Therapy
Pemphigus Vulgaris Route of Administration Outlook
- Intravenous
- Subcutaneous
- Oral
Pemphigus Vulgaris End User Outlook
- Hospitals & Clinics
- Specialty Dermatology Clinics
- Research & Academic Laboratories
Pemphigus Vulgaris Regional Outlook
- Americas
- North America
- US
- Canada
- Europe
- Western America
- Germany
- France
- UK
- Italy
- Spain
- Rest of Western Europe
- Eastern Europe
- Western America
- Asia-Pacific
- China
- Japan
- Australia
- Republic of Korea
- India
- Rest of Asia-Pacific
- Rest of the world
Available Additional Customizations
- Treatment cost analysis
- Epidemiology data
- Clinical trials data
Intended Audience
- Clinical laboratories
- Pharmaceutical market
- Government organizations
- Research & consulting firms
- Biotechnology companies
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