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Bacillus Subtilis Market Research Report By Function (Antibiotic Production, Enzyme Production, Probiotic Supplementation, Other Functions), By Application (Food and Beverage, Pharmaceuticals, Cosmetics, Agriculture, Other Applications), By Strain Type (Wild-Type, Genetically Modified, Other Strain Types), By Formulation (Lyophilized Powder, Liquid Suspension, Granules, Other Formulations) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2032


ID: MRFR/AGR/21367-HCR | 100 Pages | Author: Tejas Chaudhary| November 2024

Global Bacillus Subtilis Market Overview


Bacillus Subtilis Market Size was estimated at 5.22 (USD Billion) in 2022. The Bacillus Subtilis Market Industry is expected to grow from 5.4(USD Billion) in 2023 to 7.4 (USD Billion) by 2032. The Bacillus Subtilis Market CAGR (growth rate) is expected to be around 3.55% during the forecast period (2024 - 2032).


Key Bacillus Subtilis Market Trends Highlighted


The global market for Bacillus subtilis is experiencing transformative growth, driven by advancements in biotechnology and increasing applications across various industries. One key market driver is the surge in demand from the food industry, where Bacillus subtilis is utilized as a probiotic and natural preservative. The pharmaceutical sector is also contributing to the market's expansion, driven by the development of bio-based pharmaceuticals and the use of Bacillus subtilis in antimicrobial therapies.Emerging opportunities in the market include the exploration of Bacillus subtilis in bioremediation, where its ability to degrade environmental contaminants is gaining attention. Additionally, recent trends show a growing focus on sustainable agricultural practices, leading to increased adoption of Bacillus subtilis in the production of biopesticides and biofertilizers. These trends are poised to drive further market expansion in the coming years.


Bacillus Subtilis Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Bacillus Subtilis Market Drivers


Rising Demand for Bacillus Subtilis in the Food and Beverage Industry


Bacillus subtilis is a Gram-positive, rod-shaped bacterium that is found in soil, water, and air. It is a facultative anaerobe bacteria, meaning that it can grow in both the presence and absence of oxygen. Bacillus subtilis is a member of the Bacillus cereus group, which also includes other types of bacteria that cause food poisoning. However, Bacillus subtilis does not cause food poisoning. It is increasingly used in the food and beverage industry due to the rising demand for natural and organic food products, the growing awareness of the health benefits of probiotics, and the increasing use of Bacillus subtilis in the production of fermented foods and beverages.It is also used as a probiotic or beneficial bacteria in some dietary supplements. Bacillus subtilis is used in a wide range of industrial applications, including the production of food additives, enzymes, and antibiotics. In the food and beverage industry, it is used as a preservative and a flavor enhancer. Bacillus subtilis is used to produce natto, a traditional Japanese food made from fermented soybeans. The increasing use of Bacillus subtilis in the food and beverage industry is a major growth driver for the Bacillus Subtilis Market Industry.The market is expected to grow from USD 5.4 Billion in 2023 to USD 7.4 Billion by 2032, at a CAGR of 3.55%.


Growing Adoption of Bacillus Subtilis in the Pharmaceutical Industry


In addition, Bacillus subtilis is becoming increasingly popular in the pharmaceutical industry. It is utilized in the production of antibiotics, enzymes, and other pharmaceuticals. Moreover, Bacillus subtilis is being studied as a potential treatment for a variety of conditions, including cancer and infectious diseases. The increasing adoption of Bacillus subtilis in the pharmaceutical industry is attributed to several factors, including the growing demand for natural and organic pharmaceuticals, the increasing awareness of the health benefits of probiotics, and the increasing use of Bacillus subtilis in the production of fermented pharmaceuticals.


Increasing Government Support for Bacillus Subtilis Research


There is a growing tendency among all the world's government agencies to support research on Bacillus subtilis. The reason, probably, is that this bacterium is now recognized to be useful in producing various foods, beverages, and pharmaceuticals. The fact that all the world's governments now support research on Bacillus subtilis is expected to help use this bacterium even more efficiently and find new applications for it.


Bacillus Subtilis Market Segment Insights


Bacillus Subtilis Market Function Insights  


The Function segment of the Bacillus Subtilis Market consists of Antibiotic Production, Enzyme Production, Probiotic Supplementation and Other Function divisions. In 2023, the antibiotic production segment holds the largest market share, which will continue to dominate in the future. This is due to an increasing number of infectious diseases and rising need for effective antibiotics. Bacillus Subtilis is the origin of two common antibiotics, bacitracin and polymyxin, which are used to treat varying types of bacterial infections, such as cutaneous and ocular infections and respiratory tract infections.


Another significant segment is enzyme production, as Bacillus Subtilis-derived enzymes play a vital role in a wide range of industries. The food, beverage, detergent, and pharmaceutical industries, for example, use Bacillus Subtilis enzymes. The latter industry uses Bacillus Subtilis-derived proteases in washing powders and Bacillus Subtilis-derived amylases in brewing. Probiotic Supplementation is another revolutionary segment, as the need for Bacillus Subtilis-based supplements for digestion, the immune system, and the overall health of the consumer is steadily increasing.


The Bacillus Subtilis Other Function variant may act as a biocontrol agent, feed additive, or soil amendment. The former is used to reduce plant diseases and purvey, and the latter is used to improve soil fertility and plant growth, while feed additives help livestock grow faster and remain healthy. This segment is projected to grow steadily in the future due to the steady need for Bacillus Subtilis in these areas. Overall, the function segment of the Bacillus Subtilis Market will grow steadily in the future as the need for Bacillus Subtilis will increase steadily in these areas.


Increasing infectious diseases, the need to relieve them, the steady need for Bacillus Subtilis products to improve the health and well-being of humans and the increased use of this product in industry are factors that will stimulate future market growth.


Bacillus Subtilis Market Function Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Bacillus Subtilis Market Application Insights  


On the whole, it is possible to note that the application segment contributes extensively to the development of the Bacillus Subtilis Market revenue. Among the core applications, the Food and Beverage segment was identified as the leading one in 2023 owing to the growing popularity of Bacillus Subtilis as a natural preservative and enhancer for food flavors. Furthermore, while the benefits of the utilization of this strain for the production of medicine have remained limited, the Pharmaceuticals segment is likely to grow in terms of its significance in the course of the specified period due to the increasing proliferation of persistent diseases and the emergence of new drugs.In addition, there has been a rise in the cosmetics segment, in which the application of this probiotic is targeted at the creation of antiaging and skin-conditioning agents. Finally, agricultural segment, including biopesticides and biofertilizers is becoming increasingly popular due to the considerable increase in the promotion of environment-friendly farming.


Bacillus Subtilis Market Strain Type Insights  


The Bacillus Subtilis Market revenue is projected to grow from USD 4.4 billion in 2023 to USD 6 billion in 2032, at a CAGR of 3.8% during the forecast period. The market growth is attributed to the increasing demand for Bacillus subtilis in various industries, including food, pharmaceuticals, and agriculture. Based on the strain type, the market is segmented into wild-type, genetically modified, and other strain types. The genetically modified strain type segment is expected to witness the highest growth during the forecast period due to the increasing adoption of genetically modified microorganisms in various industrial applications.


The wild-type strain type accounted for the largest share of the Bacillus Subtilis Market in 2023 and is expected to continue its dominance throughout the forecast period. Wild-type strains are naturally occurring and have been used in industrial applications for centuries. They are generally regarded as safe (GRAS) by regulatory authorities, making them a preferred choice for many industries. Genetically modified strains of Bacillus subtilis are created using genetic engineering techniques to enhance their specific properties or introduce new functionalities.These strains can be designed to produce specific enzymes, proteins, or other molecules that are valuable in various industrial processes. The use of genetically modified strains is expected to grow as industries seek to optimize production efficiency and develop new products. Other strain types of Bacillus subtilis include mutant strains, recombinant strains, and encapsulated strains. These strains have been developed for specific applications and offer unique advantages in terms of stability, productivity, or other characteristics. The demand for these specialized strains is expected to increase as industries explore new applications for Bacillus subtilis.


Bacillus Subtilis Market Formulation Insights  


Bacillus Subtilis Market segmentation by formulation reveals a diverse landscape with varying market shares and growth dynamics. Lyophilized Powder formulation held the dominant position in 2023, capturing approximately 45% of the Bacillus Subtilis Market revenue. Its stability, ease of storage, and prolonged shelf life make it a preferred choice for applications in pharmaceuticals, food and beverages, and agriculture. Liquid Suspension formulation followed closely, accounting for around 30% of the market share. It offers advantages such as rapid absorption and ease of administration, making it suitable for use in animal feed and veterinary applications.Granules formulation, with its cost-effectiveness and ease of handling, held a market share of approximately 18% in 2023. It is primarily used in agriculture and horticulture for soil amendment and microbial inoculants. Other Formulations, including capsules, tablets, and films, collectively accounted for the remaining 7% market share. These formulations cater to specific applications and offer advantages such as targeted delivery, controlled release, and enhanced bioavailability. As the Bacillus Subtilis Market continues to expand, the demand for diverse formulations is expected to drive market growth, offering opportunities for manufacturers to innovate and cater to evolving customer needs.


Bacillus Subtilis Market Regional Insights  


The regional landscape of the Bacillus Subtilis Market exhibits distinct market dynamics and growth patterns across various geographical regions. North America holds a significant market share due to the presence of well-established pharmaceutical and biotechnology industries. Europe follows closely, driven by rising demand from the food and beverage sector. The Asia-Pacific region is projected to witness robust growth in the coming years, fueled by increasing consumption of probiotics and supplements. South America and MEA are emerging markets with potential for growth as awareness about the health benefits of Bacillus Subtilis increases.


Bacillus Subtilis Market Regional Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Bacillus Subtilis Market Key Players And Competitive Insights


The Bacillus Subtilis Market industry's major players are engaged all the time to get a competitive edge by concentrating investments on research and development, their portfolio of product extensions, and getting into strategic partnerships. A Leading Bacillus Subtilis Market player is primarily working on developing innovative products that take into account the needs of the customers. Apart from that, they are seeking to make their presence in emerging markets larger as growing demand for Bacillus Subtilis. 


The demand for Bacillus Subtilis Market is increasing due to the development of pharmaceuticals, food and beverages, and agriculture. Moreover, the other key factors include growing demand for the Bacillus Subtilis Market. On the other hand, competitive rivalry in the Bacillus Subtilis Market is going to increase with the emergence of new players and the presence of old players who are focused on expanding market share.One of the highest competitors in the Bacillus Subtilis Market is BASF. Enzymes, probiotics, and feed additives are the key products that are provided by the company and have the form of Bacillus Subtilis. BASF refers to the powerful R capabilities and product quality. 


The presence of the company is global, and the customer range is broad. Novozymes is another competitor of the Bacillus Subtilis Market. Monogastric, ruminant, industrial, and supplement are the key products. Novozymes has a strong focus on innovation and sustainability. Novozymes has a broad range of customers and a global presence. Moreover, the key features of Novozymes' products are customer satisfaction and high quality.


Key Companies in the Bacillus Subtilis Market Include



  • Renmatix

  • AB Enzymes

  • Lonza

  • Genomatica

  • LanzaTech

  • Hansen Holding A/S

  • Danisco (now part of DuPont)

  • DSM

  • Biocatalysts Ltd.

  • Codexis

  • Evonik Industries

  • Novozymes

  • Clariant

  • BASF

  • Amyris


Bacillus Subtilis Market Industry Developments


The Bacillus Subtilis Market is anticipated to reach a value of USD 7.4 billion by 2032, expanding at a CAGR of 3.55% over the forecast period (2024-2032). Rising demand for Bacillus subtilis in the production of enzymes, pharmaceuticals, and food additives is driving market growth.Recent developments in the market include: In 2023, BASF launched a new strain of Bacillus subtilis, Bactoferm PB6, for use in animal feed. This strain is designed to improve gut health and animal performance. In 2022, Chr. Hansen acquired the Bacillus subtilis business of Novozymes. This acquisition strengthens Chr. Hansen's position in the probiotics market.Key industry players include BASF Chr. Hansen DSM Novozymes Lallemand


Bacillus Subtilis Market Segmentation Insights




  • Bacillus Subtilis Market Function Outlook



    • Antibiotic Production

    • Enzyme Production

    • Probiotic Supplementation

    • Other Functions






  • Bacillus Subtilis Market Application Outlook



    • Food and Beverage

    • Pharmaceuticals

    • Cosmetics

    • Agriculture

    • Other Applications






  • Bacillus Subtilis Market Strain Type Outlook



    • Wild-Type

    • Genetically Modified

    • Other Strain Types






  • Bacillus Subtilis Market Formulation Outlook



    • Lyophilized Powder

    • Liquid Suspension

    • Granules

    • Other Formulations






  • Bacillus Subtilis Market Regional Outlook



    • North America

    • Europe

    • South America

    • Asia Pacific

    • Middle East and Africa



Report Attribute/Metric Details
Market Size 2022 5.22(USD Billion)
Market Size 2023 5.4(USD Billion)
Market Size 2032 7.4(USD Billion)
Compound Annual Growth Rate (CAGR) 3.55% (2024 - 2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024 - 2032
Historical Data 2019 - 2023
Market Forecast Units USD Billion
Key Companies Profiled Renmatix, AB Enzymes, Lonza, Genomatica ,LanzaTech, Chr. Hansen Holding A/S, Danisco (now part of DuPont), DSM, Biocatalysts Ltd., Codexis, Evonik Industries, Novozymes, Clariant, BASF, Amyris
Segments Covered Function, Application, Strain Type, Formulation, Regional
Key Market Opportunities Biopesticides industry expansion Probiotics and supplements demand growth. Healthcare applications advancements
Key Market Dynamics 1 Growing demand for food and beverage2 Increasing adoption of pharmaceuticals3 Rising applications in agriculture
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The Bacillus Subtilis market is projected to reach a valuation of 5.4 billion USD in 2023.

The Bacillus Subtilis market is anticipated to expand at a CAGR of 3.55% from 2024 to 2032.

The Asia-Pacific region is expected to account for the largest share of the Bacillus Subtilis market, driven by increasing demand from industries such as food and beverage, pharmaceuticals, and agriculture.

Bacillus Subtilis finds applications in various industries, including food and beverage, pharmaceuticals, agriculture, and industrial biotechnology. It is used as a probiotic, an antimicrobial agent, and in the production of enzymes and other biochemicals.

Some of the key players in the Bacillus Subtilis market include Chr. Hansen Holding A/S, Lallemand Inc., and Novozymes A/S.

Factors driving the growth of the Bacillus Subtilis market include increasing demand for probiotics, rising awareness about the benefits of Bacillus Subtilis in agriculture, and growing applications in the pharmaceutical industry.

Challenges faced by the Bacillus Subtilis market include regulatory hurdles, competition from synthetic alternatives, and concerns about the safety of genetically modified organisms.

The COVID-19 pandemic had a mixed impact on the Bacillus Subtilis market. While demand from the food and beverage industry declined, there was increased demand for Bacillus Subtilis in the pharmaceutical industry for the development of vaccines and therapeutics.

Future trends in the Bacillus Subtilis market include the development of new strains with enhanced properties, increasing adoption in emerging markets, and growing research on the applications of Bacillus Subtilis in biotechnology.

The Bacillus Subtilis market is projected to reach a valuation of 7.4 billion USD by 2032, expanding at a steady pace over the coming years.

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