Isothermal Nucleic Acid Amplification Market is predicted to reach USD 10.4 billion at a CAGR of 9.50% during the forecast period 2023-2032

Market Research Future (MRFR) has published on the “Global Isothermal Nucleic Acid Amplification Market”.

The Isothermal Nucleic Acid Amplification Market is estimated to register a CAGR of 9.50% during the forecast period of 2024 to 2032.

MRFR recognizes the following companies as the key players in the global Isothermal Nucleic Acid Amplification Market— Grifols, S.A. (Spain), Hologic, Inc. (US), Abbott Laboratories (US), Becton, Dickinson and Company (US), Meridian Bioscience (US), Eiken Chemical Co., Ltd. (Japan), bioMérieux SA (France), Tecan Trading AG (Switzerland), New England Biolabs (US), QIAGEN N.V. (Germany).

Market Highlights

The global Isothermal Nucleic Acid Amplification Market is accounted to register a CAGR of 9.50% during the forecast period and is estimated to reach USD 10.4 billion by 2032.

The increasing incidence of infectious illnesses is largely responsible for the noticeable increase in demand for the molecular testing method known as isothermal nucleic acid amplification technology, or INAAT. Hepatitis, influenza, and tuberculosis are some of the most common infectious disease-related causes of mortality, particularly in underdeveloped nations. Therefore, it is anticipated that the desire for quick, easy-to-use, and disease-specific testing alternatives will increase the use of INAAT solutions.

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Segment Analysis

The global Isothermal Nucleic Acid Amplification Market has been segmented based on the Product, Technology, Application, and End-User.

Based on the Product, the market is segmented into Assays, Kits, & Reagents, and Systems. The Assays, Kits, & Reagents segment was attributed to holding the largest market share in 2023. Enzymatic dissociation involves the utilization of enzymes to break down tissue fragments, liberating cells from the tissue. Various types of enzymes are employed in this process, and they can also be combined. Enzymatic dissociation methods offer a more efficient and effective approach to isolating mononuclear cells from both the spinal cord and the brain.

Based on the Technology, the Isothermal Nucleic Acid Amplification Market has been segmented into transcription-mediated amplification (TMA), Loop-mediated Isothermal Amplification (LAMP), Strand Displacement Amplification (SDA), Helicase-dependent Amplification (HDA), Nucleic Acid Sequence-based Amplification (NASBA), Nicking Enzyme Amplification Reaction (NEAR), Single Primer Isothermal Amplification (SPIA), and Other Technologies. The Loop-mediated Isothermal Amplification (LAMP) segment was expected to hold the largest market share in 2023. The Loop-mediated isothermal amplification (LAMP) test stands out as the most widely utilized technique, with its adoption expected to surge significantly in the forecast period. This method employs a minimum of four primer sets, consisting of two outer primers and two inner primers. Several software tools, including Primer Explorer and LAMP Designer, aid in primer design. These loop primers bind to the nucleic acid template, expediting the reaction process. Notably, the LAMP technique facilitates the amplification of both DNA and RNA. Since its introduction in the early 2000s, LAMP tests have been extensively adapted for various pathogenic agents, owing to their ability to amplify both DNA and RNA. Furthermore, these tests find utility in identifying genetically modified organisms.

Based on the Application, the Isothermal Nucleic Acid Amplification Market has been segmented into Disease Diagnosis, Blood Screening, and Other Applications. The Blood Screening segment was expected to hold the largest market share in 2023. Several factors, including the increasing demand for blood transfusions and the subsequent need for blood testing worldwide, are expected to positively influence the growth of this segment by 2030. INAAT is extensively employed for assessing blood quality through the screening of transfused blood for the presence of infectious agents. Moreover, the escalating research endeavors aimed at creating INAAT devices capable of detecting molecular biomarkers and multiple blood-borne pathogens are poised to expand the market's growth opportunities.

Based on the End-User, the Isothermal Nucleic Acid Amplification Market has been segmented into Hospitals, Reference Laboratories, Academic & Research Institutes, and Other End Users. The Hospitals segment was expected to hold the largest market share in 2023. The rise can be credited to the advancement of compact point-of-care INAAT devices, facilitating streamlined access for hospital-based analysis. Likewise, the enhanced throughput and automation capabilities provided by these technologies for handling extensive sample volumes are anticipated to drive growth in the segment.

Regional Analysis

The global Isothermal Nucleic Acid Amplification Market, based on region, has been divided into North America, Europe, Asia-Pacific, and the Rest of the World. North America consists of the US and Canada. The Europe Isothermal Nucleic Acid Amplification Market comprises Germany, France, the UK, Italy, Spain, and the rest of Europe. The Isothermal Nucleic Acid Amplification Market in Asia-Pacific has been segmented into China, India, Japan, Australia, South Korea, and the rest of Asia-Pacific. The Rest of the World's Isothermal Nucleic Acid Amplification Market comprises of Middle East, Africa, and Latin America.

The largest market share for the Isothermal Nucleic Acid Amplification Market was maintained by the North American regional sector. North America commands the Isothermal Nucleic Acid Amplification Technology (INAAT) market, driven by several factors including a high prevalence of chronic diseases, advancements in isothermal nucleic acid amplification technology, and the growing preference for INAAT over conventional methods in the region. As per data from the Centers for Disease Control and Prevention (CDC), in 2020, approximately 157 million Americans were estimated to have chronic illnesses, with 81 million experiencing multiple conditions. Similarly, GLOBOCAN 2020 reported 2,281,658 new cancer cases diagnosed in the United States in the same year, resulting in 612,390 fatalities.

Moreover, the Europe market has been persistently growing over the forecast period. Isothermal amplification methods play a significant role in diagnosing infectious diseases by swiftly and accurately detecting pathogens like viruses and bacteria. This capability is crucial for effectively managing diseases, conducting surveillance, and controlling outbreaks. In 2022, England and Wales recorded a total of 577,160 deaths, marking a decrease of 9,174 deaths (1.6%) compared to 2021. However, it also represented an increase of 33,747 deaths (6.2%) compared to the five-year average spanning from 2016 to 2019 and 2021. Ischaemic heart disease remained the leading cause of death among males in 2022, accounting for 38,730 deaths (13.3% of all male deaths registered). Similarly, dementia and Alzheimer's disease retained their position as the leading cause of death among females, with 42,635 deaths recorded (15.0% of all female deaths registered). This pattern remained consistent from the previous year, 2021.

The Asia-Pacific region is anticipated to experience the highest growth rate, driven by an increase in the average disposable income of individuals and the expansion of modernized healthcare infrastructure. India's public healthcare expenditure rose to 2.1% of GDP in FY23 and 2.2% in FY22, compared to 1.6% in FY21, as reported in the Economic Survey 2022-23. The Indian medical tourism market, valued at US$ 2.89 billion in 2020, is projected to reach US$ 13.42 billion by 2026. According to the India Tourism Statistics at a Glance 2020 report, nearly 697,300 foreign tourists arrived for medical treatment in India during FY19. India secured the tenth position in the Medical Tourism Index (MTI) for 2020-21 among 46 destinations, according to the Medical Tourism Association. With a Medical value travel (MVT) market size of US$ 5-6 billion and serving 500,000 international patients annually, India stands as one of the leading global destinations for international patients seeking advanced medical treatment

Furthermore, the rest of the world's Isothermal Nucleic Acid Amplification Market is divided into the Middle East, Africa, and Latin America. Governments and public health organizations in these regions are increasingly investing in disease control and surveillance programs. Isothermal amplification technologies play a vital role in these initiatives by providing efficient and cost-effective diagnostic tools for disease monitoring, surveillance, and outbreak response.

Key Findings of the Study

• The global Isothermal Nucleic Acid Amplification Market is expected to reach USD 10.4 billion by 2032, at a CAGR of 9.50% during the forecast period.


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  The Asia-Pacific region accounted for the fastest-growing global market owing to the high incidence of chronic diseases, and technological advancement in isothermal nucleic acid amplification technology.
  


• Based on Product, the Assays, Kits, & Reagents segment was attributed to holding the largest market in 2023.


• Grifols, S.A. (Spain), Hologic, Inc. (US), Abbott Laboratories (US), Becton, Dickinson and Company (US), Meridian Bioscience (US), Eiken Chemical Co., Ltd. (Japan), bioMérieux SA (France), Tecan Trading AG (Switzerland), New England Biolabs (US), and QIAGEN N.V. (Germany) are the key market players.